Dragonfly Therapeutics is Hiring a Principal Associate Scientist/Senior Principal Associate Scientist, Hit Identification and Biology Near Waltham, MA
Principal Associate Scientist/Senior Principal Associate Scientist, Hit Identification and Biology Dragonfly Therapeutics seeks an experienced and motivated Principal/Senior Principal Associate Scientist with a strong background in cell biology/immunology to support the discovery and development of cancer and autoimmune therapies. The successful candidate will work with Dragonfly's Hit Identification Team developing cell reagents and performing functional screening assays. In addition, the candidate will assist the flow cytometry core manager with daily operations and maintenance. The individual will support the Biology group in the pre-clinical development of novel biologic drugs that promise to revolutionize disease treatment. Responsibilities:
Maintain mammalian tissue culture, including adherent/suspension cell lines and primary cells
Execute cell line engineering workflows (CRISPR, viral transduction, transfection) to support antibody discovery and screening/characterization
Drive the development and implementation of cell-based screening and characterization assays to support therapeutic candidate selection
Perform multi-color cytometry experiments and data analysis
Assist with the daily operations of the flow cytometry core, including performing scheduled instrument maintenance
Analyze, interpret and communicate laboratory results within Hit ID team, the Biology group and Research department
Manage daily work flow independently and seek advice when appropriate
Maintain a detailed and up to date electronic lab notebook
Qualifications:
BS or MS degree in Cell Biology, Immunology, Bioengineering or relevant field (title commensurate with years of experience)
3 years of relevant research experience; industry experience (1 years)
Strong understanding of immunology and cellular engineering
Expertise in mammalian cell culture and cell engineering using CRISPR and transduction/transfection techniques.
Experience with flow cytometry, cell sorting, and analysis of flow cytometry data is preferred
Strong organizational and time-management skills
Excellent verbal and written communication and interpersonal skills to work across functions
Ability to work within a team, coordinating with other scientists
Self-motivated, conscientious, and enthusiastic about helping patients
About Dragonfly Dragonfly Therapeutics is a clinical-stage biopharmaceutical company committed to discovering, developing and commercializing therapies that use its novel multispecific antibody technology to harness the body's immune system to bring breakthrough treatments to patients. In addition to its wholly owned clinical assets, Dragonfly has a deep pipeline of wholly owned preclinical candidates discovered using its proprietary platform, as well as productive collaborations with Merck, AbbVie, Gilead and Bristol Myers Squibb in a broad range of disease areas. Our mission is to revolutionize disease treatment by inventing natural killer cell-based therapies for vastly improved patient outcomes. We believe in a small team with a big impact.