Company Overview. Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue. Dyne has a broad pipeline for serious muscle diseases, including clinical programs for myot...
Role Summary. The Co-Op in the Neuromuscular Research Group will be trained in a variety of lab techniques and will support analysis of biological samples. The individual will be an integral team member and contribute to the understanding of molecular and cellular phenotypes of in vitro and in vivo models of neuromuscular diseases, discovery and characterization of potential therapeutic compounds using relevant models. The individual will have th...
Role Summary. The Associate Director, Clinical Scientist is a key member of the Clinical Development team for the planning, conduct, analysis, and reporting of clinical studies. The person in this role plays a key role in designing, implementing, and managing clinical trials to evaluate novel therapies for patients with rare muscle diseases. The person in this role works independently and in collaboration with the Clinical Development Lead and ot...
Company Overview. Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue. Dyne has a broad pipeline for serious muscle diseases, including clinical programs for myot...
Company Overview. Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue. Dyne has a broad pipeline for serious muscle diseases, including clinical programs for myot...
Company Overview. Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue. Dyne has a broad pipeline for serious muscle diseases, including clinical programs for myot...
Role Summary. The position is responsible for product development, technology transfer and overall management of CMC activities related to ensuring robust development and reliable GMP supply of oligonucleotide conjugates and intermediates. Depending on the product phase, the person in this role will provide both guidance and active management of conjugated drug substance in Phase 1 thru BLA and commercial production. This includes coordinating ex...
Role Summary. The Senior Director, Drug Safety and Pharmacovigilance will play a key leadership role in characterizing the safety profiles of Dyne products and mitigating and communicating their risks throughout the product lifecycle (from First-In-Human to post-marketing). This role will provide short- and long-term strategic leadership of safety surveillance for Dyne’s clinical development programs, including resource planning and long-range ca...
Role Summary. As a member of the Platform Oligo innovation team, the successful candidate will contribute to the development of Dyne’s oligonucleotide chemistry platform and enable the discovery of novel oligonucleotide therapeutics. This individual will be responsible for building an internal oligonucleotide chemistry lab and will lead the design, synthesis, purification, and analysis of oligonucleotides and their conjugates. The position requir...
Role Summary. In this role, the Head of Compliance will design, implement, and administer a comprehensive compliance program appropriate to the size and stage of Dyne that is scalable as Dyne transitions to a commercial stage company. The Head of Compliance also will act as the primary resource for healthcare law legal counseling across the entire organization. The person in this role will work with our CEO and Board of Directors. This role is b...
Role Summary. The Director, Regulatory Affairs helps drive forward our regulatory strategy and operational activities related to Dyne’s muscle disease programs. The person in this role must thrive working in a fast-paced environment where flexibility, accountability and fearless innovation are key. Additionally, this individual must have excellent interpersonal skills, ability to develop important relationships with key stakeholders, good conflic...
Company Overview. Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue. Dyne has a broad pipeline for serious muscle diseases, including clinical programs for myot...