The Company
We are Alloy Therapeutics-a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of its revenue in innovation and access to innovation. MAY THE BEST DRUG WIN.
Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, CH; and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture. Come thrive at Alloy!
The Team
The Alloy RNA Medicines group is innovating a novel RNA-based drug discovery platform, namely "AntiClastic", spanning the fields of antisense therapeutics to immunomodulating therapeutics. The team works closely with external partners to discover and develop AntiClastic RNA medicines.
The Role
As a Senior Scientist, you will work within the RNA Medicine team to develop a novel nucleic acid drug development platform. You will also collaborate with internal/external partners on nucleic acid drug discovery projects to ensure timely execution of the experiments, and delivery of high-quality data. This role requires a self-starting behavior with an enthusiasm and passion to make medicines. This role will have an autonomy owning various stakeholders, projects, and tasks in a dynamic start-up environment while keeping up the pace of Alloy. This is you!
How You'll Drive Impact

• Innovate : Lead multiple drug discovery and development projects. Develop novel methodologies to elucidate the mechanism of action of AntiClastic RNA Medicines
• Improve : Learn and identify key questions in the RNA medicine area
• Deliver : Spearhead drug discovery projects, Design, execute, analyze, and interpret in vitro and in vivo experiments. Generate robust, high-quality data.
• Collaborate : Work closely with internal/external partners on drug discovery projects to ensure studies are executed to meet scientific goals and timelines.

Why We Value You

• You have a PhD or M.S. degree in Biology or related science with 5 to 8 years of additional experience in biotech/pharma.
• Independently design, execute, and analyze in vitro experiments.
• Strong understanding of antisense/siRNA research
• Ability to improve and develop new protocols/new assays to address key questions
• Ability to interact and collaborate successfully in cross-functional teams
• You have experience with RNA therapeutic development, from early discovery to pre-clinical development.
• You have strong hands-on experience with molecular biology and protein techniques including, but not limited to, nucleic acid isolation, qPCR, RT-qPCR, western blots.
• You have experience with cell culture and cell-based assays.
• You have a keen attention for detail.
• You have effective interpersonal skills, including both written and oral communication skills.

Desired Multipliers

• Excitement and willingness to learn.
• Ability to work across various US and international time zones
• Accommodate occasional travel as needed (<10%)

Taking Care of Our People
We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together, we focus on programs and benefits that support a diverse and growing team. Whether you're single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one.
Compensation

• Competitive base and equity compensation
• 401(k) company match and financial planning
• Unlimited PTO (paid time off) and flexible schedules

Health & Family

• Generous personal and family medical, dental and vision benefits with 90% of premiums and deductibles covered
• Company-paid disability (STD, LTD) and life insurance
• Paid parental leave
• Family planning support up to $50,000 (e.g. IVF/PGT, adoption, surrogacy, egg retrieval)

Unique Perks

• Flexible work schedule built around our team-driven philosophy
• Annual stipend for continuing education with commitment to your career through individualized professional development plan
• Extensive Employee Assistance Program (EAP) including resources for mental wellness
• International travel insurance

Diversity, Equity, and Inclusion
Here at Alloy, we democratize capabilities for discovering and developing therapeutic biologics. So, being diverse and inclusive isn't just something we strive for, it is who we are, and part of what we do each and every single day. We want to ensure that as an employee, you feel Alloy is a place where, no matter who you are, you feel safe, included, and that you have the opportunity to bring your unique self to work.

Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at [email protected]. We will make every effort to respond to your request for disability assistance as soon as possible.