Salary: Negotiable :USD

Location: Chicago, IL

Hospital: RUSH University Medical Center

Department: Neurological Sciences-Res Adm

Work Type: Full Time (Total FTE between 0.9 and 1.0)

Shift: Shift 1

Work Schedule: 8 Hr (8:00:00 AM - 4:30:00 PM)

Summary: The Research Associate will design and perform complex scientific research experiments. This person will be involved in creating symptoms and pathology in mice similar to multiple sclerosis. The position will utilize knowledge of proteomics, molecular biology, neurobiology, cell biology, biochemistry, and animal brain surgery. This person will troubleshoot and evaluate data, and prepare manuscripts based on experimental results. The work requires the application of highly specialized knowledge of neuroinflammation and neurodegeneration. Some of the related techniques that may be applied in the research to be conducted will include: microinjection, mass spectrometry, high-throughput screening, mammalian cell culture, cell transfection assays, flow cytometry (FACS), immunoprecipitation/Western blots. He will be also involved in training one PhD student. Exemplifies the Rush mission, vision and values and acts in accordance with Rush policies and procedures.

Responsibilities: • Mentoring a PhD student • Maintaining and breeding transgenic mice • Establishing a mouse model of multiple sclerosis by tail-vein injection of autoreactive T cells • Creating a new mouse model of multiple sclerosis by RANTES intoxication • Intranasal, intraperitoneal and oral treatment of mouse models of multiple sclerosis by different drugs • Monitoring locomotor activities of mouse models of multiple sclerosis before and after drug treatment • Examining the levels of different genes and protein in the brain • Culturing different brain cells • Assaying activities of different T lymphocytes • Animal transcranial perfusion and histology. • Performing immunohistochemistry and confocal/bright field microscopy • Statistical analysis of data analysis • Prepare abstracts and manuscripts • Write grants

Other information: Required Job Qualifications: • Ph.D. with expertise in neuroinflammation and neurodegeneration focusing on multiple sclerosis • T cell activation, tail vein injection, student mentoring, and manuscript writing • Ability to work for 8 hours daily in the lab. Disclaimer: The above is intended to describe the general content of and requirements for the performance of this job. It is not to be construed as an exhaustive statement of duties, responsibilities or requirements.

Rush is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other legally protected characteristics.