Position overview Position title: Assistant Researcher Salary range: Salary will be commensurate with experience and based on UC Berkeley Researcher series salary scale. Percent time: 100% Anticipated start: November 1, 2022 Position duration: 1 year with the possibility of extension based on performance and funding availability. Application Window
Open date: September 6, 2022
Next review date: Wednesday, Sep 21, 2022 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.
Final date: Thursday, Oct 6, 2022 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Position description
The Innovative Genomics Institute (IGI) is a multidisciplinary research laboratory focused on genome engineering and potential applications in agriculture, microbiology, and biomedicine. It is a joint venture between UC Berkeley and UC San Francisco, with the administrative operations located on the Berkeley campus. This position is located at the UC Berkeley campus.
The IGI is presently seeking a highly motivated Research Scientist to develop independent research programs focused on developing an organoid center of excellence in conjunction with genome editing discovery, therapeutic candidate selection, automated robotic tissue culture, and other areas of IGI innovation. Specific goals include combining humanized organoid/in vitro model systems with IGI platforms for editor development/optimization, such as bone marrow/blood models to test in vivo delivery for hemoglobinopathies; lung organoids and air liquid interface models to screen cystic fibrosis and respiratory virus therapeutic candidates; gastrointestinal/colon organoids to understand cancer progression and screen potential genomic interventions; and patient-derived liver organoids to assess mutation pathogenicity.
The Research Scientist will collaborate with other investigators at UCB and IGI in the use of organoids and 2D in vitro models to rigorously screen and advance genomic editing therapeutic candidates Occasional travel will be required.
This position is represented by UAW 5810 RA Academic Researchers and is covered by a collective bargaining agreement.
Qualifications Basic qualifications (required at time of application)
PhD (or equivalent international degree).
Additional qualifications (required at time of start)
5 years of postdoctoral experience.
Preferred qualifications
PhD or equivalent international degree in Chemical, Biological Engineering, Molecular Genetics, Cell Biology, Biochemistry.
Experience in organoids, disease models, animal experiments, and gene- and transcript-based characterization of models/animals.
Experience with genome editing applications; ability to screen, test, and optimize genome editing tools in organoid model systems.
Experience developing organoid and 2D cell models from primary and stem cells.
Experience using genome editing to create genetically valuable or distinct organoid models.
Experience representing or recapitulating human disease, including but not limited to, cancer, infectious disease, gut microbiome dysbiosis, and neurodegeneration.
Experience with long-term cultivation of organoid systems.
Experience evaluating biologics or small molecules in organoid tumor and other disease models.
Experience generating patient-derived organoid models for detailed functional characterization.
Experience designing and executing studies to profile candidate molecules in organoid systems.
Experience troubleshooting technical difficulties associated with organoid establishment, growth, and testing.
Experience growing multiple types of mammalian organoids and extensive knowledge of media and growth factors required for successful organoid cultivation.
Experience writing, leading, and managing grants, and securing own funding.
Experience with mentorship of undergraduates, graduate students, and/or technicians.
The ideal candidate will have the demonstrated ability to effectively communicate, participate in efficient and open in collaboration, and enjoys engaging with a diverse group of researchers. The ideal candidate will also be innovative and able to synergize various ideas and approaches, while exercising sound judgment to evaluate and take acceptable risks
Application Requirements Document requirements
Curriculum Vitae - Your most recently updated C.V.
Cover Letter (Optional)
Statement on Contributions to Advancing Diversity, Equity, and Inclusion - Statement on your contributions to diversity, equity, and inclusion, including information about your understanding of these topics, your record of activities to date, and your specific plans and goals for advancing equity and inclusion if hired at Berkeley (for additional information go to https://ofew.berkeley.edu/recruitment/contributions-diversity ).
Reference requirements
3-5 required (contact information only) Apply link: https://aprecruit.berkeley.edu/JPF03602
Help contact: rachelkevans@berkeley.edu
Campus Information
Diversity, equity, inclusion, and belonging are core values at UC Berkeley. Our excellence can only be fully realized by faculty, students, and academic and non-academic staff who share our commitment to these values. Successful candidates for our academic positions will demonstrate evidence of a commitment to advancing equity, inclusion, and belonging.
The University of California, Berkeley is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see: http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct
In searches when letters of reference are required all letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality ( http://apo.berkeley.edu/ucb-confidentiality-policy ) prior to submitting their letter.
As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy. All Covered Individuals under the policy must provide proof of Full Vaccination or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, and/or Religious Objection) or Deferral (based on pregnancy) no later than the applicable deadline. Please refer to Appendix F, Section II.C. of the policy for the deadlines applicable to new University of California employees. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.
Positions that are represented by a collective bargaining unit or agent have particular contracts. For more information, please refer to the relevant contract: Lecturer contract , Postdoctoral contract , Research Series contract , and Librarian contract . Questions about represented positions can be directed to the hiring unit.
Job location Berkeley, CA
To apply, visit https://aprecruit.berkeley.edu/JPF03602
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