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Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people's varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.
The PositionWe are seeking a passionate Principal Systems Engineer to join our Systems Development Group to support the Next Generation Sequencing (NGS) products. This role is expected to be a hands-on key contributor in feasibility, integration, development, verification and validation phases of end-to-end NGS solution. Hands-on development experience of at least one of the programming languages such as Python, C for hardware automation or statistics analysis applications. Working knowledge of bioinformatics workflows including demultiplexing, alignment, variant calling, etc.
Responsibilities:
This position is responsible for, but not limited to, the following:
Perform systems development activities as part of the project team to develop new NGS solutions and ensure the product design meets customer needs as well as applicable regulations or standards. May serve as the Systems representative on cross-functional teams and efforts.
Participate in developing, and managing large subsystem-level or system-level product requirements, critical parameter management (CPM), configuration management, and traceability analysis.
Develop, execute, and document test cases for verification and validation. Ensure complete and comprehensive coverage of requirements in the test campaign.
Plan and prioritize activities /assignments to guide junior team members.
Perform systems integration and testing activities to verify system performance through simulation, tests, and measurements. Assess results for applicability, validity, and conformance to product requirements.
Work independently with general management direction to drive product development and collaborations to identify opportunities for continuous improvement.
Perform product risk management activities using tools such as Hazard Analysis or Failure Modes and Effects Analysis (FMEA) according to Roche's applicable regulatory and quality standards and provide risk mitigation recommendations to the project team.
Collaborate with project teams and internal/external stakeholders to create project artifacts and maintain related documents in Design history files.
Keep supervisor/project leader informed of project status, particularly of significant findings and results in critical problem areas.
Who you are
You're someone who wants to influence your own development. You're looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.
Qualifications:
wet lab experience.
BS, MS or equivalent experience in engineering, sciences, or related field or Ph.D with 5 years related experience with thorough technical knowledge proven leadership skills, and proven
record of accomplishments. Prefer MS, PhD. with 8-10 years of experience.
Strong data analysis skills using standard analysis software (e.g. with JMP) and able to determine how best to represent it visually to managers and stakeholders.
Hands-on development experience of at least one of the programming languages such as Python, C for hardware automation or statistics analysis applications.
Hands-on experience using linux based operating systems and linux command line interfaces
Experience with systems reliability is highly desirable.
Hands-on troubleshooting experience with hardware and software is highly desirable.
Experience using automated (SW) testing tools to drive systems integration is desirable.
Comprehensive knowledge and understanding of End to End workflow in NGS space with a focus on instrumentation and automation
Working knowledge of bioinformatics workflows including demultiplexing, alignment, variant calling, etc.
Experience with cloud deployment is desirable.
Strong analytical, problem-solving, communication, and interpersonal skills and a fast learner to work in a diverse team environment.
In addition to impeccable technical skills, successful candidates possess strong organizational, communication and team skills, and thrive in a fast-paced environment
Resourceful and flexible; fast learner and a self-starter; hard-working
Adept at planning, prioritizing, multi-tasking, organizing and following through, while remaining highly energetic and focused;
Straightforward, self-driven, and trustworthy;
An individual with experience in biotechnology or medical device development;
Breadth of knowledge / cross-disciplinary
troubleshooting experience with instrumentation, SW, and NGS workflow.
Strong analytical, problem-solving, communication, and interpersonal skills and a fast learner.
Desired:
Anticipates needs and problems while creating solutions. Not always instruction-based
Demonstrates a sense of urgency, contagious optimism and a "can do" attitude
Is curious, inquisitive, innovative, never satisfied with the status quo
Greets challenge and change as opportunity
Collaborates with others and strong orientation towards teamwork
Relocation benefits are not offered for this role. The expected salary range for this position based on the primary location of Santa Clara, CA is $128,120 and $161,595. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed here:
Who we areAt Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form .
Roche is an Equal Opportunity Employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status.Full Time
Pharmaceutical
$191k-218k (estimate)
03/15/2024
05/17/2024
roche.com
SOUTH SAN FRANCISCO, CA
15,000 - 50,000
1976
Private
FRANZ B HUMER
$5B - $10B
Pharmaceutical
Genentech is a biotechnology company that discovers, develops and commercializes medicines to treat patients with life-threatening medical conditions.
The job skills required for Principal Systems Engineer include Troubleshooting, Planning, Futures, Leadership, Python, Problem Solving, etc. Having related job skills and expertise will give you an advantage when applying to be a Principal Systems Engineer. That makes you unique and can impact how much salary you can get paid. Below are job openings related to skills required by Principal Systems Engineer. Select any job title you are interested in and start to search job requirements.
The following is the career advancement route for Principal Systems Engineer positions, which can be used as a reference in future career path planning. As a Principal Systems Engineer, it can be promoted into senior positions as an Enterprise Infrastructure Manager that are expected to handle more key tasks, people in this role will get a higher salary paid than an ordinary Principal Systems Engineer. You can explore the career advancement for a Principal Systems Engineer below and select your interested title to get hiring information.