The Clinical Research Coordinator (CRC) manages and conducts the day-to-day activities of a clinical trial . The Principal Investigator (PI) determines the CRC's specific responsibilities and works closely with the CRC. In general, the CRC ensures the clinical study maintains accordance with the protocol, applicable regulations, and Good Clinical Practice (GCP) and Institutional Review Board (IRB) requirements. Beyond administrative duties, responsibilities of a CRC may include acting as a liaison for the clinical site, ensuring staff are properly trained per the protocol, recruiting and/or registering participants, maintaining study guidelines, and collecting and/or reviewing the data or review before it is entered into a study database .