Description

Marengo Therapeutics, Inc., a clinical-stage biotech company, develops novel TCR-targeting antibodies that selectively modulate common and disease-specific T cell subsets of the germline TCR repertoire to provide lifelong protection against cancer and other diseases. With a passionate team of dedicated scientists experienced in immunology and oncology, Marengo’s proprietary Selective T Cell Activation Repertoire (STAR) platform leverages an extensive biological understanding of T cell function and receptor signaling to create a world in which everyone’s immune system can defeat cancer. To learn more, visit marengotx.com.

About STAR0602

STAR0602 is Marengo’s lead program, the first selective T cell activator generated from Marengo’s STAR platform; a library of antibodies targeting non-clonal variable (V)ß regions of the TCR fused to different co-stimulatory moieties. STAR0602 selectively targets a common Vb T cell subset present in all cancers and, by combining a novel non-clonal mode of TCR activation with a T cell co-stimulator in the same molecule, promotes expansion of a new population of clonally enriched, effector memory Vb T cells that turbo-charge immune system and promote a durable anti-tumor immune response. STAR0602 has undergone extensive preclinical testing, which demonstrates potent anti-tumor activity in both mouse and human ex vivo tumor models attributed to a distinct mechanism of action from existing cancer immunotherapies.

Requirements

Purpose of the role:

The lab & facilities manager will be responsible for the day-to-day operational function of our growing clinical-stage company. Our team is looking for a highly motivated and hands-on individual primarily responsible for lab management, including onsite materials and equipment management, EH&S procedures, and broad facility coordination. This team member will own, lead & execute the function responsibilities and provide professional support to our entire organization.

Who are we looking for?

· You are an energetic and passionate lab and office operations professional who likes to think outside of the box, challenge the norm, and is passionate about the company’s mission of discovering and developing new medications

· You are a resourceful self-starter and team player with a strong result orientation

· You consider yourself a guru in all the critical lab operations in a clinical-stage organization

· You can develop trusting relationships to gain support and achieve results at all levels of the organization

What are we looking for?

· A driven professional who knows how to work and contribute to an ever-changing working environment

· A collegial individual who enjoys working in close collaboration with leaders in the research, development, quality, clinical, and administrative areas of the company

· A willingness to learn new things, adapt to new ways and go with the flow

· A person who thrives in a small company atmosphere

· Ability to determine task priority and maintain established deadlines

What are we offering?

· Membership within a growing, CARING, and collegial organization

· Being part of a passionate, involved, and cutting-edge Operations Team

· Exposure to pioneering science and the discovery of drugs to help treat patients with cancer

Responsibilities:

· Manage material in the lab to ensure continuous efficient operation of the company (ordering, inventory tracking, receiving, shipping, stocking, and organizing lab supplies, biohazard waste management, LN, and CO2 tanks change)

· Facilitate laboratory reorganization/expansion, including moves, redesigns, and equipment installations

· Liaise with EH&S and other vendors to ensure lab compliance (risk assessment, annual MSDS and chemical inventory update, biohazard waste management, safety training, and application and renewal of lab permits)

· Prioritize and address IT issues reported by employees and organize IT support as required

· Lab and office equipment life cycle management, including purchase and commissioning of new equipment, periodic maintenance & calibration, moves, asset tag, and decommissioning through effective partnerships with internal service partners and external service providers

· Coordinating and managing planned system outages and coordinating large-scale projects impacting the facility and being the lead for management of alarm systems, including restoration, resets, and checks

· Be part of our team to onboarding new employees in the lab and IT needs

Education and Experience:

· Minimum of 7 years of progressive, relevant experience in the biopharma or medical device industry required

· BA/BS in relevant science or related field

· Understand regulatory requirements (e.g., GLP) and MA state biological and chemical permit requirements

Strong attention to detail and exceptional interpersonal, organizational, and communication skills.

Flexibility to work early or late hours in case of lab emergencies

Competencies:

Adaptability: Responds resourcefully, flexibly, and positively when faced with new challenges, transitions, and demands. Willingly and effectively deals with the stress and complexities of various situations. Moves forward productively and optimistically under conditions of change and uncertainty.

Collaboration: Embodies and promotes collaboration and works effectively with others across the organization to achieve goals. Demonstrates proficient cross-company communication, cultural sensitivity, and partnership in interactions with others. Involves others in decisions and plans and credits them for their contributions and accomplishments.

Execution: Drives execution of strategic and operating plans while maintaining operational effectiveness. Conveys a strong sense of urgency around continuous improvement, achieving high-quality results, and accelerating business performance. Addresses problems directly and drives changes necessary to achieve business objectives.

Relationship Building: Establishes and maintains strong relationships internally and externally. Respects and relates well to management, colleagues, peers, and direct reports. Champions a culture of respect, diversity, and inclusion that values and respects individuals. Earns the respect of others through principled leadership, sound business ethics, and authenticity.

Location: Cambridge, MA ( We are located in Lower Cambridge, called Cambridgeport)

When You Join Marengo, You Will Have:

• Free parking, Cambridge location reachable by public transportation (Red Line)

• Customized and competitive health coverage, including medical offered through BCBS (PPO), dental, and vision

• Flexible Spending Accounts for medical and dependent care expenses

• Eligible from the first day for 401K, no matching

• A robust package of Marengo-paid insurance coverage, including life insurance, short-term and long-term disability

• 20 days of vacation and one personal days per year, in addition to 13 company holidays and one floating holiday

TO ALL AGENCIES: Please, no phone calls or emails to any employee of Marengo about our openings. All resumes submitted by search firms/employment agencies to any employee at Marengo via email, the internet or in any form and/or method will be deemed the sole property of Marengo unless such search firms/employment agencies were engaged by Marengo for this position and a valid agreement with Marengo is in place. In the event a candidate who was submitted outside of the Marengo agency engagement process is hired, no fee or payment of any kind will be paid.

Marengo Therapeutics, Inc. is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service or any other class protected by state or federal law.