Summary:

We’re looking for an individual with a solid background in molecular biology and analytical science. The candidate will work as a part of a collaborative team to generate analytical data for R&D and drug development. The candidate must be detail oriented, have excellent record keeping and communication skills, and be willing to work in a dynamic entrepreneurial environment with a deep interest in bringing a new type of gene therapy to patients.

Responsibilities include:

• Become a critical part of our gene therapy analytical workflow
• Work closely with other scientists to advance drug discovery and clinical development
• Precise record keeping including electronic lab notebook writing
• Both follow and develop analytical assays including those suitable to monitor the manufacture and release of viral vectors and other products
• Assist in the characterization of processing steps for yield, product integrity and
  clearance of impurities
• Support stability programs
• Author standard operating procedures, development reports and regulatory documentation
• Assist in technology transfer to CDMO and CROs
• Work with external service providers, including supporting the communication.

Skills, qualifications, and experience:

• BS or MS in Biology, Molecular Biology, Biochemistry, or a related discipline with 2 years laboratory research experience
• Strong laboratory skills and a high degree of attention to detail with the experience in following molecular biology and analytical techniques:
  • PCR, gel electrophoresis, gel imaging, SDS-PAGE
  • Mammalian cell culture, transfection, transduction (AAV)
  • Nucleic acid preparation (DNA, RNA), ddPCR, qPCR and data analysis
• Passion for working at the bench to advance programs
• Self-motivation and adaptability to evolving project priorities and responsibilities
• Team-oriented, effective communication skills with a strong work ethic
• QC analytics (especially AAV), highly desired

Additional skills/experience beneficial, but not required:

• Virus production (especially AAV)
• Other analytical techniques such as ELISA, HPLC, ELISPOT assay