Advanced Bio-Logic Solutions Corp is Hiring a Scientist Senior Near Thousand Oaks, CA
Top 3 Must Have Skill Sets:
Significant experience in bioinformatics, applied mathematics and/or statistics, including linear mixed effects models, to analyze multi-modal, multi-dimensional and large-scale biological data
A working knowledge of platforms and readouts utilized for the assessment of clinical biomarkers including flow cytometry, IHC, NGS, immunoassays, imaging, and transcriptional profiling assays
Programming experience in Python & R and familiarity with tidyverse principles
Ability to translate biological and medical questions into analytical models providing actionable results
A working knowledge and experience of Machine Learning and AI technologies. Experience applying ML/AI in clinical trial settings is a plus.
Familiarity with assay development and qualification requirements for clinical trial support
Ability to work in a highly matrixed environment and drive scientific and technical innovation collaboratively with other members of the group, as well as with Amgen research community
Three or more years of relevant experience in the biotech or pharmaceutical industry
Strong written and oral communication skills, self-motivation, independence, and leadership
Day to Day Responsibilities:
Support the development of clinical biomarkers supporting Amgen programs through the formulation and execution of biomarker data analysis
Perform assessment of biochemical coverage, patient stratification, indication selection in Amgen’s early and late clinical development programs and discovery of clinical insights at asset and portfolio levels through the application of knowledge discovery and data mining techniques
Develop translational informatics analysis workflows in a high-content, multi-omics, multi-modal data domain encompassing genomics, transcriptomics, proteomics, metabolomics and epigenomics domains
Work with biologists, especially in immuno-oncology, to leverage information on targeted biological pathways along with development of computational algorithms to manage and mine internal and external genomics and other high-content databases
Provide leadership and expertise to the function in the areas of algorithm development, bioinformatics, data integration & management, visualization, analysis, and presentation
Interface cross-functionally with the early development teams, assay laboratories, in-vitro diagnostics, and biomarker representatives
Red Flags:
Limited programming experience or lack of formal training in quantitative discipline
Early preclinical experience only
Interview Process:
Hiring manager phone screen
Short take-home programming exercise
45 minute candidate seminar on prior research experience
1:1s with 3-4 members of the hiring team
PAY RATE : Open rate. on W2 "This posting is for Contingent Worker, not an FTE"