Are you passionate about Life Science and want to contribute to life changing research? Then take the chance to perform you master thesis with us at AstraZeneca! Project description: The AZ developed physiological based biopharmaceutic model (PBBM) GI-Sim, is frequently used to assess the interplay of various biopharmaceutics properties of different APIs and formulations during drug development. The GI-Sim tool incorporates both pre-clinical models (rat, dog, mouse) and human models (fed & fasted). During the last few years, the pig has become an often used pre-clinical species in PK and tox studies and hence the development of a pig model in GI-Sim is highly needed. During this Master thesis you will review the literature and collect data on the physiology of the pig, i.e. GIT volumes, transit times, permeability, micelle concentrations etc. Based on the collected data the student will build a Pig model(s) in GI-Sim and validate the model(s) with in-house PK data from previous studies. Essential Requirements: Ongoing Master studies in relevant area - pharmaceutics, bioscience or similar. So, what’s next? Apply today and take the chance to be part of making a difference, making connections, and gaining the tools and experience to open doors and fulfil your potential. We can´t wait to hear from you! Last application date: 2024-05-31 Why AstraZeneca? AstraZeneca is a global, innovation-driven biopharmaceutical company that focuses on the discovery, development, and commercialization of prescription medicines for some of the world's most serious diseases. In addition to being one of the world's leading pharmaceutical companies, AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. Within this environment employees are empowered to express diverse perspectives, and are made to feel valued, energized and rewarded for their ideas and creativity. Date Posted 07-maj-2024 Closing Date 30-maj-2024 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.