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Postdoctoral Fellowship

National Institutes of Health
Bethesda, MD Full Time
POSTED ON 11/2/2025
AVAILABLE BEFORE 12/1/2025

A postdoctoral fellowship at the NIH is available to study metabolism and development in the Section on Gamete Development (SGD) in the intramural program of the NICHD. The SGD uses Drosophila oogenesis to study basic question in how cells maintain metabolic homeostasis in the context of a developing multicellular organism. The NIH provides excellent training opportunities including access to genomic and proteomic core facilities, and state of the art imaging.

About the position

In the last ten years, studies primarily performed in tissue culture cells have defined the role of the Gap Activity Towards Rag (GATOR) Complex in the response to acute amino acid limitation. However, relatively little is known about the detail regulation and function of the GATOR complex in vivo. Using Drosophila as a model, the SGD aims to define the pathways that regulate the GATOR-TORC1 signaling in the context of a multicellular animal. The major objectives of our work include:

  • Obtain a mechanistic understanding of how the GATOR2 complex controls TORC1 activity and lysosomal homeostasis; and
  • Determine how TORC1 signaling regulates early meiotic events and oocyte differentiation to ensure oocyte quality and genome stability over time.

To achieve these goals our laboratory uses a combination of genetic, molecular and cell biological techniques including CRISPR/CAS9 genome editing and super-resolution imagining.


What you'll need to apply

To apply please send your CV, a statement of research interests and contact information for three references by email to Mary Lilly email: lillym@nih.gov .

Contact name

Mary Lilly

Contact email

lillym@nih.gov

Qualifications

We are seeking an enthusiastic candidate with a strong publication record and less than four years postdoctoral experience that has either a Ph.D. or M.D. equivalent. A strong background in molecular biology as well as experience in biochemistry and/or Drosophila biology is required.

Disclaimer/Fine Print

U.S. citizens and permanent residents are eligible to apply.

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