What are the responsibilities and job description for the Postdoctoral Fellow - cancer biology, functional genomics position at National Institutes of Health?
The Neuro-Oncology Branch (NOB) at the National Cancer Institute’s Center for Cancer Research (CCR) is a specialized program focused on the study and treatment of brain and central nervous system (CNS) tumors. We are seeking an outstanding candidate to join our Molecular and Cell Biology (MCB) Program.
About the position
This position involves investigating the unique metabolic phenotype and molecular signaling in brain tumors. The research aims to systematically explore epigenetic changes in cancers, characterizing critical epigenetic targets within DNA repair, metabolism, and therapy resistance pathways using genetic and biochemical approaches. Mechanistic findings will be verified through in vitro and in vivo models, patient-derived specimens for validation, and experimental therapeutics design based on preliminary findings. These discoveries will provide strong justifications for future clinical translation and application.
Position Highlights:
- Outstanding Training: Combine basic mechanistic research with disease-relevant preclinical research.
- Advanced Models: Utilize both mouse models, patient-derived xenografts (PDXs), and human specimens to develop next-generation therapeutics.
- Collaborative Medicinal Research: Work in a dynamic, collaborative, and interdisciplinary research team. State-of-the-Art Resources: Access state-of-the-art research facilities and resources, including equipment, computational tools, and reagents.
- Exciting Research Environment: Benefit from well-equipped in-house core facilities and intense collaborations among laboratories.
- Expert Mentorship: Receive guidance from renowned scientists and clinicians, gaining invaluable knowledge in the field.
What you'll need to apply
- CV/Resume
- 3 References
- Summary of Research Experience
Contact name
Chunzhang Yang
Contact email
yangc2@nih.gov
Qualifications
- Degree Required - Ph.D. or equivalent
- Interested and motivated to investigate fundamental questions in cancer biology and functional genomics.
- Leverage a background in biochemistry and molecular biology, emphasizing signal transduction, cancer cell biology, cell cycle, or DNA repair.
- Collaborate with the Principal Investigator (PI) for hypothesis development, experimental design, and execution.
- Participate in data processing, analysis, discussion, reporting, presenting findings at conferences, and manuscript drafting.
- Work effectively within an interdisciplinary team.
- Stay informed of developments in the field to maintain and enhance professional expertise.
- Perform lab maintenance, including equipment upkeep and supply ordering.
- Teach techniques to train and mentor junior research staff.
- Demonstrate excellent communication skills and fluency in both spoken and written English.
Disclaimer/Fine Print
U.S. citizens and permanent residents are eligible to apply.