Demo

Principal Engineer

Bayer
St. Louis, MO Full Time
POSTED ON 9/4/2026
AVAILABLE BEFORE 12/26/2026
At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where 'Health for all Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining ‘impossible’. There are so many reasons to join us. If you’re hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there’s only one choice. Principal Engineer Principal Engineer for St. Louis, MO to lead IT project strategies in software architecture & development of digital, data, and AI solutions, leveraging cloud-native, event-driven, and serverless architectures; lead teams in implementing & operating secure, scalable, and resilient architectures for automation, observability, and self-service platforms; design & implement real-time data, analytics, and AI solutions; mentor & train engineers. Requires Master’s degree in C.S., Software Engineering, Electrical Engineering or closely related field & 3 yrs experience in a consumer health, life sciences and/or pharmaceutical environment: designing & operating GxP Lakehouses in compliance with 21 CFR Part 11 and EudraLex Annex 11 using AWS Sagemaker Unified Studio, Databricks, and Microsoft Fabric; implementing Zero-Trust and Governance-as-Code to automate security controls; using Terraform to automate Installation Qualification and Operational Qualification documentation within CI/CD and/or DevSecOps pipelines and regulatory workloads; designing & implementing real-time Agentic AI strategies and life sciences business flows for autonomous reasoning and RAG implementations; scaling AI-MLOps using SageMaker, EKS, and/or Databricks, including Federated Learning & Explainable AI for clinical validation; leading application of Differential Privacy, Safety & Federated Learning to patient datasets for cross-border AI training; managing engineering delivery & excellence within Global Capability Centers. Telecommuting permissible from home office location within reasonable commuting distance of St. Louis, MO up to 2 days per week. Up to 20% U.S. and int’l travel req’d. Salary Range: Employees can expect to be paid a salary between $190,000.00 to $225,000.00. Additional compensation may include a bonus or commission (if relevant). Additional benefits include health care, vision, dental, retirement, PTO, sick leave, etc. The offered salary may vary within this range based on an applicant’s location, market data/ranges, an applicant’s skills and prior relevant experience, certain degrees and certifications, and other relevant factors. Mail resume to Jill Martin, Bayer U.S. LLC, 800 N. Lindbergh Blvd., E2NE, St. Louis, MO 63167 or email resume to careers_us@bayer.com. Include reference code below with resume. | ---|--- YOUR APPLICATION| | Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Health for all, Hunger for none, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer. To all recruitment agencies: Bayer does not accept unsolicited third party resumes. Bayer is an Equal Opportunity Employer/Disabled/Veterans Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below. | ---|--- Equal Opportunity Employer Statement: Notice for U.S. Visitors: All information on this site is subject to compliance with local rule and regulations as they may vary from time to time and across different geographies, including, without limitation, U.S. Executive Orders.| | Bayer is an E-Verify Employer.| | | | Location:| United States : Missouri : St. Louis | Division:| Enabling Functions | Reference Code:| 873561 | | --- Contact Us | Email:| careers_us@bayer.com

Salary : $190,000 - $225,000

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