Research Technician II, Molecular Biology, Buszczak Lab

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Molecular Biology

The Molecular Biology Department at UT Southwestern mission is to conduct high-impact internationally recognized research, and to educate and train the next generation of leaders in biomedical research. The research in Molecular Biology focuses on understanding mechanisms that control normal and abnormal cell growth and differentiation during development and disease.

Job Summary 

The Bassel-Duby Lab is seeking to hire a Research Technician II. As part of the Olson lab, the scientific focus is on muscle cells as a model for understanding how stem cells adopt specific fates and how programs of cell differentiation and morphogenesis are controlled during development. We have discovered many of the genes that control heart and muscle development and disease, including transcription factors, microRNAs, microproteins, and the stress-response pathways. Recently, we have identified two novel proteins Myomaker and Myomixer that are essential for myoblast fusion and skeletal muscle development. 

We are interested in the mechanisms of heart repair and regeneration. We have discovered that the neonatal mouse heart has remarkable regeneration capacity upon injury, which is lost within the first week of life. Using multiomics sequencing combined with spatial transcriptomics, we generated an atlas for the transcription basis of neonatal heart regeneration at single-cell resolution. Our ultimate goal is to utilize the regenerative signals and transcription factors identified from the atlas from different cell types in the heart to repair the injured adult heart and enhance cardiac function after injury.

Experience and Education

• Bachelor's degree with major coursework in field of assignment and no experience required.
• Two (2) years college with emphasis in coursework in field of assignment and two (2) years of laboratory experience at level of Laboratory Technical Assistant or equivalent.
• High school graduation or GED and four (4) years laboratory experience to include two (2) years at level of Laboratory Technical Assistant or equivalent.

Lab Duties

• Maintain and wash glassware for multiple PI laboratories within the Molecular Biology Department.
• Operate all equipment in the prep room, including washers, driers, and autoclaves.
• Maintain, oversee, and organize common areas in the department.
• Perform basic, routine procedures as prescribed by supervisor.
• Autoclaving biohazard material and keeping records.
• Communicating guidelines and compliance information to laboratories.
• Coordinating service calls and keeping Department Manager advised of service issues and status of repairs. Also, alerting user labs of service down times.
• Order or ensure that necessary supplies are ordered and inventoried to maintain adequate stock.
• Other duties as assigned.

Job Duties

• Performs routine scientific and medical research work in science area such as biology, chemistry, physics, or other related scientific field.
• Assembles and/or operates various laboratory equipment and apparatus.
• Records research data in accordance with prescribed procedures, discussing results with supervisor.
• Assists in collection of data for project reports.
• Reads literature and confers with supervisor concerning implementation of new procedures.
• May plan for, and provide working supervision to, work of laboratory personnel of lower grade engaged in limited phase of research project.
• Performs other duties as assigned.

To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.