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Full Time 40 hours Grade 075 Dept of Biomedical Genetics

Schedule

8 AM-4:30 PM

Responsibilities

POSITION DESCRIPTION:

The individual will be part of a research team working to understand the role of viruses in Alzheimer disease using cutting edge technologies. Duties will include laboratory work related in the field of neurological disease, with a focus on Alzheimer's. Among other neurological diseases, our lab studies the role of latent viral infections on Alzheimer Disease. Our approach uses both animal models of AD, as well as in vitro pluripotent stem cell models of human patient-derived cells. The individual will perform a variety of moderately complex laboratory experiments. Position requires excellent organizational skills and attention to detail. College level training in biological sciences is desirable. With an excellent track record in placing prior team members, our lab and this position is uniquely suited as a launching point for research (PhD) or medicine (MD), and enables entry into a future career in regenerative medicine (both academia and industry).

Procedures performed and equipment used:

Alzheimer model mouse colony maintenance, genotyping, histology. Tissue dissection, cell isolation and purification, cell culture procedures and genetic manipulation of cells. RNA isolation and RT-QPCR, protein isolation, gel electrophoresis, image capture and analysis (CX5), immunofluorescent analyses. No involvement in the assessment, treatment or care of patients is involved with this work.

Supervision:

This position reports to Dr. Margot Mayer-Proschel, Ph.D.. After a period of initial guidance and training, this position requires that the individual be able to execute experiments independently, analyze data, and help troubleshoot results. This person will also occasionally help train and/or guide others in existing lab techniques.

RESPONSIBILITIES:

• Helps to maintain mouse animal colonies: routine animal mating and husbandry logs, genotyping of offspring, tissue harvest and histology.
• Plans and performs a variety of cellular and molecular experiments and analyses investigating human disease biology including but not limited to: analysis of cell division and survival, gene expression analysis, genetic modification of cells using transient transfection and lentiviral vectors, drug screening and in vitro modeling of neural cell functions.
• Performs routine cell culture preparations of human and rodent neural tissue, human embryonic stem cells and induced pluripotent stem cells.
• Maintains detailed lab journal. Records and calculates results. Presents data in prescribed formats.
• Extracting from data, literature searches and existing resources to come up with reasoning to interpret experimental observations or problems that may be encountered. Uses theoretical knowledge to trouble shoot experiments and equipment malfunctions. Independence in problem solving is highly encouraged.
• Performs general laboratory duties such as preparing reagents and re-stocking supplies and maintenance of cryopreservation systems. Helps to ensure laboratory compliance for biosafety, EHS and fire inspections. Other job duties and tasks as assigned.
• Provides assistance and training for incoming students.
• Participates in lab and research meetings.

Other duties as assigned

QUALIFICATIONS:

Required Qualifications:

• High school diploma.
• One year experience performing basic sampling, monitoring, or research activities, compiling and collecting data, and preparing reports. Or equivalent combination of education and experience.

Preferred Qualifications:

• BA/BS in Biochemistry, Chemistry, Biology, Neuroscience, Biomedical Engineering, or a related field.
• Highly motivated, ability to multitask, good organizational abilities, and ability to work well as part of a team.Strong interpersonal and communication skills, including written communication.

The University of Rochester is committed to fostering, cultivating, and preserving a culture of equity, diversity, and inclusion to advance the University's mission to Learn, Discover, Heal, Create - and Make the World Ever Better. In support of our values and those of our society, the University is committed to not discriminating on the basis of age, color, disability, ethnicity, gender identity or expression, genetic information, marital status, military/veteran status, national origin, race, religion/creed, sex, sexual orientation, citizenship status, or any other status protected by law. This commitment extends to the administration of our policies, admissions, employment, access, and recruitment of candidates from underrepresented populations, veterans, and persons with disabilities consistent with these values and government contractor Affirmative Action obligations.

How To Apply

All applicants must apply online.

EOE Minorities/Females/Protected Veterans/Disabled

Pay Range

Pay Range: $15.38 - $21.54 Hourly

The referenced pay range represents the minimum and maximum compensation for this job. Individual annual salaries/hourly rates will be set within the job's compensation range, and will be determined byconsidering factors including, but not limited to, market data, education, experience, qualifications, expertise of the individual, and internal equity considerations.