Research Lab Specialist Intermediate/Research Lab Specialist Associate

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**How to Apply**

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

**Summary**

Candidates interested in either leading their own projects or supporting projects of other team members are encouraged to apply. Excellent opportunity for individuals interested in studying stem cells and tissue regeneration as well as immune-epithelial crosstalk. Projects range from basic mechanistic to translational. Opportunities to learn cutting-edge techniques, including organoid culture and scRNAseq. Opportunities for career development, including manuscript and grant writing and oral presentation, mentorship, attending international conferences, interacting with renowned scientists who are collaborators.

**Mission Statement**

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

**Who We Are**

Our lab is interested in understanding the mechanisms by which the lung epithelium responds to injury. We study mechanisms of injury/inflammation and regeneration after injury. Epithelial injury and a failure of epithelial regeneration is thought to drive the development of lung diseases such as ARDS (including COVID-19), fibrosis, and emphysema. Specifically, we are exploring the mechanisms underlying proliferation and differentiation of alveolar epithelial progenitor or stem cells. We have identified ?-catenin, HIF, and TGF? signaling as important drivers. We also study the epithelial inflammatory and host defense responses to bacterial and viral infection, specifically epithelial-immune cell crosstalk. We use mouse and cell culture models to study mechanisms. The mouse work involves lineage tracing and inducible cell-specific gene deficient mice, and primary epithelial cell culture/organoid work allows us to further dissect mechanism. We use confocal imaging, immunostaining, fluorescence in situ hybridization (FISH), single cell RNA sequencing, proteomics, and flow assisted cytometry sorting (FACS). We aim to address important questions and make novel discoveries that significantly enhance our understanding of lung biology and disease. We hope that our discoveries may ultimately lead to the development of therapies for infectious, inflammatory, and fibrotic lung diseases.

**Why Join Michigan Medicine?**

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world's most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

**What Benefits can you Look Forward to?**

Excellent medical, dental and vision coverage effective on your very first day

2:1 Match on retirement savings

**Responsibilities***

This individual will be expected to take a leading role and work closely with the PI in the development and implementation of this research program.

Perform mouse experiments

Perform in vitro experiments

Write protocols

Prepare manuscripts & grants

All other duties as assigned

**Required Qualifications***

A PhD (completed or near completion) or MS or BS with significant experience in cell biology, developmental biology, immunology, physiology, or related field is required.

Outstanding organizational skills, attention to detail, ability to work hard and be flexible in a fast-paced environment, and ability to get along with other lab members are important.

At least one first authored manuscript in a peer-reviewed journal is required for candidates with a PhD.

Intermediate Requirements: 4-5 years related experience

Associate Requirements:1-3 years related experience

**Desired Qualifications***

Prior experience with rodents, cell culture, microscopy, RNA/qPCR, western blotting, computational biology, and/or flow cytometry would be helpful.

**Underfill Statement**

This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.

**Background Screening**

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

**Application Deadline**

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

**U-M EEO/AA Statement**

The University of Michigan is an equal opportunity/affirmative action employer.

**Job Detail**

**Job Opening ID**

247078

**Working Title**

Research Lab Specialist Intermediate/Research Lab Specialist Associate

**Job Title**

Research Lab Specialist Inter

**Work Location**

Ann Arbor Campus

Ann Arbor, MI

**Full/Part Time**

Full-Time

**Regular/Temporary**

Regular

**FLSA Status**

Exempt

**Organizational Group**

Medical School

**Department**

MM Int Med-Pulm./Critical Care

**Posting Begin/End Date**

4/02/2024 - 5/04/2024

**Career Interest**

Research

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