POSITION SUMMARY:

The Pryciak Lab seeks a highly motivated research associate to study the recognition of short peptide motifs by globular protein domains. The project aims to reveal the molecular specificities of these peptide motif binding interactions and how they can be tuned to control the magnitude and timing of molecular reactions in the cell, including substrate identification by post-translational modification enzymes. See PubMed ID 32976810 and the Pryciak Lab website for further information: https://www.umassmed.edu/pryciaklab/

Familiarity with molecular biology methods (DNA preparation, plasmid sub-cloning, PCR) and/or microbiological culture of E. coli or S. cerevisiae are advantageous but not required.

Under the direction of the Principal Investigator (PI) or designee, the Research Associate I provides operational support to the laboratory. The Research Associate I will perform research experiments as defined by the PI.

ESSENTIAL FUNCTIONS:

Perform laboratory experiments and may be responsible for a single research project
• Utilize all software relevant to experiment and equipment used
• Interpret data, form conclusions and decide on next steps under the direction of the PI or designee
• Maintain accurate records, may modify protocols with the approval of the PI or designee
• Review literature, publications and grants relevant to assigned projects
• Record results according to established lab, sponsor & university protocol
• Assist with performing data analysis and/or mathematical computations
• Maintain a detailed lab notebook according to lab practice
• Present findings at lab/group meetings
• Monitor laboratory supply levels and order as noted
• Prepare and label buffers, media, solutions, etc.
• Assist with and comply with all safety regulation and infection control standards
• Train on IACUC, IRB, EHS, Radiation safety protocols
• Comply with all applicable state, federal university, and sponsor policies and agreements
• Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions
• Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
• Perform other duties as required

REQUIRED QUALIFICATIONS:

• Bachelor's degree in Biological or Natural Science, or equivalent experience
• Basic understanding of lab safety and protocols
• Knowledge of Microsoft Office products
• Ability to analyze data in a quantitative and objective manner.
• Ability to work in a team environment