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General Summary of Position
The Abdennur Lab at UMass Chan Medical School is seeking applications for a highly skilled and motivated Postdoctoral Researcher to join our dynamic team. The successful candidate will have a strong background in epigenetics and/or 3D genomics, computational biology, and machine learning. The successful candidate’s research will involve mining, exploration, integrative analysis, physical or statistical modeling, and visualization of large and multimodal data sets derived from next-generation sequencing technologies, leveraging both public data and experimental data from collaborators. This is an exciting opportunity to contribute to cutting-edge collaborative research with an emphasis on mapping and deciphering the biological roles of novel chromatin states. Opportunities for hands-on lab bench or software engineering experience are possible.
About the Abdennur Lab
We are a team of computational biologists and engineers developing both foundational and cutting-edge genomic data science tools and applying them to answer fundamental questions in 3D and functional genomics. We value tinkerers, interdisciplinary thinkers, and people with a passion to use their skills for scientific discovery. The Lab was founded in 2022 at the University of Massachusetts Chan Medical School, in the Department of Genomics and Computational Biology. We have active research collaborations with experimental investigators and are members of large collaborative initiatives, including the NIH 4D Nucleome (4DN) consortium and the newly established NIH Multi-Omics for Health and Disease (MOHD) consortium.
About the PI
Dr. Nezar Abdennur received his PhD in Computational and Systems Biology at MIT, specializing in the spatial organization of the genome (3C/Hi-C technologies), its relationship to the epigenome, and its influence on gene regulation. His postdoctoral work expanded to profile diversity in silent chromatin states and how they change in disease. His work has contributed to the discovery and understanding of the biophysical processes shaping genomes and has laid foundational open-source software for 3D genome analysis. He co-founded Open2C, a community of computational biologists developing open-source software for chromosome biology, with regular contributors from multiple institutions worldwide. He is also a co-developer of HiGlass, a visualization platform for interactive, multiscale, and multimodal exploration of (epi)genomic information, and Oxbow, a bioinformatic file interoperability library.
Major Responsibilities:
Qualifications:
Application Instructions:
Interested candidates should submit the following documents as a single PDF file to abdenlab@umassmed.edu
Review of applications will begin immediately and will continue until the position is filled. Only shortlisted candidates will be contacted for further evaluation and interview.
SUPERVISION RECEIVED
Under the direction of the PI.
SUPERVISION EXERCISED
Mentoring and supervising graduate students and junior lab members.
ENVIRONMENTAL WORKING CONDITIONS
Hybrid/remote work within the USA is allowed. Separate office space (to be shared with other members of the lab) for on-site work.
Other
$87k-110k (estimate)
03/13/2024
03/08/2025
umassmed.edu
AMHERST, MA
3,000 - 7,500
1962
LAWRENCE FELDMAN
$50M - $200M
Massachusetts first and only public academic health sciences center is made up of three graduate schools and two business units, Commonwealth Medicine and MassBiologics. Perennially ranked among the top medical schools for primary care education by U.S. News & World Report, UMass Medical School is also an international leader in biomedical research, with $399 million in NIH funding in FY 2020. UMass Medical School educates physicians, scientists and advanced practice nurses to heal, discover, teach and care with compassion. Our researchers are making discoveries daily in the fight against dise...ases such as ALS, Tay-Sachs, COVID-19, cancer and diabetes. UMass Medical School strives to advance the health and well-being of the people of the commonwealth and the world through pioneering education, research and health care delivery with clinical partner UMass Memorial Health. Commonwealth Medicine provides a wide range of care management and consulting services to government agencies, nonprofits and health care organizations, improving health care for people in need while also maximizing revenue for clients and performing cutting edge research that impacts health policy. MassBiologics, the only nonprofit, FDA-licensed manufacturer of vaccines and biologics in the United States, improves public health through applied research, development and production of biologic products, including vaccines, plasma derivatives and monoclonal antibodies.
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