The group of Dr. Mike Sasner has an opening for a full-time position as a Research Assistant. This position will focus on developing and characterizing novel models of Alzheimer’s disease, as well as reporter models useful for research in neurodegeneration. This role requires experience using mouse models, including colony maintenance and genotyping. Experience with immunohistochemistry and an educational background in Neurobiology preferred. This position is a great opportunity to develop independent projects while working within the MODEL-AD Center. Key Responsibilities: RA I: Conducts tests, experiments, and/or procedures following standard or detailed protocol; identifies and documents variations that may affect the validity of the experiment. Data collection and analysis. Performs quality control, monitors data for accuracy, uploads data to database system within agreed upon timelines with supervisor. Validate and conduct studies based upon standard experimental protocols within the agreed upon timelines with supervisor/technical manager. Ensure functionality and maintenance of instrumentation. Records all information, daily, in an official laboratory notebook RA II: Identifies problems, troubleshoots and analyzes variations observed and reported in regular testing protocols; modifies, refines or adapts techniques and procedures; modifies and/or adjusts quality control measures. Monitors documentation of results; reviews and recognizes documentation which may lead to modification and adaptation of research methodologies; may collaborate with others. Plans and monitors resources needed to operate the laboratory; maintains inventory control; coordinates space, field, equipment and/or facilities; may monitor expenditures. Leads exchange of research information through demonstration and instruction. Assists in grant writing and proposal development. Conducts multiple experiments and is responsible for maintenance of equipment used in those experiments. Is organized, responsible and reports results clearly and efficiently to supervisor. Records all information, daily, in an official laboratory notebook Requirements: RA I: Bachelor’s degree in biological sciences or related discipline OR 1-3 years of related experience. RA II: Bachelor’s degree in biological sciences or related discipline OR 3 – 6 years of directly related experience in a Laboratory setting. Mouse handling and husbandry skills required. Both levels: Experience with immunohistochemistry and an educational background in Neurobiology preferred. Fundamental computer skills, including familiarity with Excel and Word. Ability to clearly and concisely communicate information verbally and in written form. Strong attention to detail is required. Must be a strong team-player and posses excellent listening skills. Ability to work flexible shifts (evening/week-end/holiday) About JAX: The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine! EEO Statement: The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.