Scribe Therapeutics is a molecular engineering company focused on creating best-in-class in vivo therapies that permanently treat the underlying cause of disease. Founded by CRISPR inventors and leading molecular engineers Benjamin Oakes, Brett Staahl, David Savage, and Jennifer Doudna, Scribe is overcoming the limitations of current genome editing technologies by developing custom engineered enzymes and delivery modalities as part of a proprietary, evergreen CRISPR by Design™ platform for CRISPR-based genetic medicine.

We are seeking a highly creative, passionate, and motivated individual to join us in our quest to develop the next generation of CRISPR-based therapeutics. The current role is for a Senior Research Associate, Molecular Engineering to join our team and advance our platform. The candidate should have a passion for working collaboratively with biologists and bioengineers to enable building the necessary tools for meeting the new frontier of CRISPR-based therapeutics. Additionally, the candidate would bring expertise in molecular biology and cell culture.

The candidate will have numerous opportunities for professional growth in a rapidly growing biotechnology start-up, which includes growing into a leadership role of increasing responsibilities and the ability to publish highly impactful work in peer reviewed journals. 

Key Responsibilities:

• Work closely with the engineering team to screen and characterize CRISPR molecules to advance activity, specificity, and novel functionality
• Execute the necessary molecular biology, tissue culture, biological assays, and related data processing and analysis
• Help the team design and execute hypothesis-driven and properly controlled studies and analyze data
• Effectively collaborate with members within a fully integrated team to facilitate execution on projects within established timelines
• Effectively present data and communicate research plans and timelines to the core team
• Foster a driven, fast-paced, dynamic, and fun environment in which to do rigorous science

Required Skills and Background:

• A BS/BA in Bioengineering, Cell or Molecular Biology, Synthetic Biology, or related discipline
• 3-5 years wet lab research experience & previous industry experience required
• High level of proficiency in mammalian cell culture (transfection, gDNA harvest, cell line generation), flow cytometry, and high throughput workflows
• Experience with NGS library prep
• Exemplify our values of integrity, creativity, drive and pragmatism
• Excellent communication and organizational skills
• Ability to work both independently and collaboratively in a fast-paced, interdisciplinary research team

Preferred Skills and Background:

• Post-graduate studies are a plus
• Experience with CRISPR-Cas gene editing systems and delivery technology desired
• Experience with pooled screening techniques
• Experience with lentiviral transduction and mRNA transfection
• Familiarity with protein or RNA structure and engineering approaches

Salary will be commensurate with experience. We will provide an intellectually stimulating, collegial and fast-paced environment. If you are ready to engineer the future of therapeutics, then we are excited to hear from you! Visit us at www.scribetx.com.

We are committed to creating a diverse environment and are proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, disability, age, or veteran status.

At the time of posting, the base pay wage range for this role is $80,000-110,000 per year. The offered pay range will depend on internal equity and the candidate’s relevant skills, experience, qualifications, training, and market data. Additional incentives are provided as part of the complete package in addition to comprehensive medical and other benefits.