The Principal Scientist functions as a subject matter expert and has direct oversight to ensure successful implementation, execution, and completion of non-clinical studies. The individual filling this position must have extensive Good Laboratory Practice (GLP) experience and must be able to influence best practices. The Study Director will assume the responsibility for the technical conduct of a particular study as well as the interpretation, analysis, documentation and reporting of study results. Primary Responsibilities Include: Serves as Study Director on GLP and nonGLP toxicology studies and oversees all technical and scientific study conduct and deliverables through study completion. Ensures all applicable GLP standards/ regulatory (FDA 21 CFR Part 58) are followed. Assures adequate test materials and test systems are available. Provides nonclinical expertise to a cross-functional study team. Works with internal functional areas to ensure all studies are performed in a high quality, timely and scientific manner. Designs protocols and ensures that the protocol and amendments are approved before work is executed. Disseminates notifications of study, protocol, and amendments/deviations to study personnel and QAU Authors, updates, and/or reviews area-specific SOP's and Protocols, ensuring that documents reflect current processes Ensures accurate documentation of study results and representation of study results Ensures archival of data in a timely manner Leads/participates in continual improvement initiatives May take on other tasks/initiatives identified by management as appropriate Desired Education and Skills: BS/BA, MS/MA, or PhD in relevant scientific discipline with 15 , 12 , or 9 years of related experience, respectively Must have at least 5 years of experience working in a GLP environment in the biopharmaceutical industry as a Study Director Must be proactive, collaborative, responsive, and diligent Excellent communication (verbal, written, and presentation) and people skills Ability to adapt to a fast-paced and dynamic biotech environment and overcome challenges with a positive “can-do” attitude Willingness to learn and contribute Highly organized and able to work with great precision and attention to detail Experience with statistical and computer productivity software (eg Provantis) Proven ability to manage multiple projects/tasks at one time #LI-Onsite This position requires work on site at one of Sarepta’s facilities in the United States. The targeted salary range for this position is $133,200 - $166,500 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify. Sarepta is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development. Our vast pipeline is driven by our multi-platform Precision Genetic Medicine Engine in gene therapy, RNA and gene editing. For more information, please visit www.sarepta.com or follow us on Twitter, LinkedIn, Instagram and Facebook.