Summary of the JobValidation and routine execution of a range of in vitro ADME assays including permeability, metabolic stability, tissue/protein binding, solubility, drug-drug interaction, and in vivo PK studies, including study design, sample preparation, sample analysis using LC-MS/MS, and data report to support drug discovery and development for clients. Implementation of new technologies/sciences within the areas of expertise to improve the data quality of the studies in screen and selection of drug candidates.
Duties and Responsibilities

• Comply with all the Standard Operating Procedures applicable to the job tasks.
• Conduct assays and sample preparations following established procedures to support drug discovery programs of the clients.
• Operate LC-MS for compound tuning, method development, and sample analysis.
• Assist development of new assays to help improve service capabilities.
• Assist troubleshooting of the issues/problems arisen from the assays and execute solutions for problem solving.
• Maintain detailed records and notebooks to assist method/report writing and data interpretation.
• Train other scientists in running established assays.
• Required to work in the laboratory that has a certain level of noise and contains hazardous chemicals.

Qualifications:

• PhD in Biology, Chemistry or related discipline with greater than 2 years, Master’s Degree with greater than 5 years, or Bachelor’s Degree with greater than 8 years’ experience in a laboratory environment
• Expertise in advanced experimental methods including cell culturing skills as well as the concepts and techniques relevant to scientific discipline.
• Scientific/technical independence and creativity.
• Ability to expand knowledge in the relevant scientific discipline through related scientific literature.
• Ability to conduct researches collaboratively and propose methodologies for projects.
• Attention to detail and awareness of potential impact from any concerns.
• Good at written communication and oral presentation