Over one million people in the world today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many patients, the transplant itself can prove fatal or lead to serious conditions, such as graft versus host disease.

Orca Bio's investigational, high-precision cell therapies are designed to replace a patient's compromised blood and immune system with a healthy one, while dramatically lowering the risk of developing life-threatening or debilitating transplant-related side-effects. The first application of Orca Bio’s platform is in blood cancer where the unmet need is most acute; with a robust pipeline of promising cell therapies, we plan to extend into autoimmune diseases and genetic blood disorders as well.

In this one-year assignment, with possibility for extension, we are looking for recent Ph.D graduates to lead projects focused on studying the fundamental biology of regulatory T cells (Tregs) and their role in immune regulation following adoptive transfer.

Key responsibilities include:

- Investigating the cellular and molecular mechanisms underlying Treg function in inflammation and autoimmunity.

- Utilizing in vitro cell-based assays and mouse models to advance our understanding of Treg biology.

- Collaborating with interdisciplinary teams to explore therapeutic opportunities for autoimmune diseases and immune-related disorders.

Required Qualifications:

• Ph.D. in Immunology, Molecular Biology, Cell Biology, or related field.
• Strong background in Treg or T cell biology and immunology.
• Experience with in vitro cell-based assays and mouse models.
• Demonstrated ability to independently design, execute, and interpret experiments.
• Excellent communication and interpersonal skills.
• Track record of scientific productivity, including peer-reviewed publications, is desirable.

The anticipated annual salary range for this U.S. based job is $75,000– $100,000. The final offer will be based on professional experience previously in this role/industry, education, geographic location, internal equity, and other job-related factors as permitted by law. For remote-based candidates, this range may vary based on your local market. Actual compensation may vary. You will also be eligible to receive pre-IPO equity, in addition to medical, dental, vision, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Total compensation will be determined at the Company's sole discretion.

Who we are

We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all patients who need them.

We strive to do things right, and to embody our core values of passion, courage, and integrity. Excellence in our work means the potential to unlock a better quality of life for our patients, and with that comes tremendous responsibility.

We innovate daily on a path that hasn’t been paved. This means we lean heavily on our entrepreneurial spirit and are comfortable taking calculated risks to achieve progress toward our mission. It means we aren’t afraid to ask “why not,” and encourage lively discourse around rethinking the status quo.

We work hard to preserve our start-up culture rooted in camaraderie and leadership by example - by everyone, regardless of title.

We’re proud to be an equal opportunity employer, and have seen how our differences - when celebrated and woven together - create stronger and more lasting solutions that better serve our team, our partners, and most importantly, our patients and the providers who treat them.

Notice to staffing firms

Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent department, and all candidates are presented through this channel only. We do not accept unsolicited resumes.