MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of 350 dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer.Our products and platforms have attracted multiple partnerships with leading pharmaceutical and biotechnology companies around the globe.

MacroGenics is a bold, highly engaged, and diverse team driven by a passion for improving the lives of patients through innovative science. We are committed to an inclusive workplace built on trust and respect. We value and nurture strong connections with one another and foster collaborative relationships. We empower our people and drive personal accountability. We encourage curiosity and embrace our entrepreneurial spirit. We celebrate our successes and create a learning environment where all employees can thrive!

Summary of Position

The Intern will be working in the Antibody Engineering Department of MacroGenics, implementing techniques in protein production and purification to produce membrane proteins encapsulated in nanodiscs, synthetic model membrane systems, for use in antibody discovery and in vitro assays. The intern will be responsible for establishing protocols for nanodisc generation as well as producing nanodiscs containing protein targets of interest.

Responsibilities and Job Duties

• Develop experimental plans/protocols with guidance, execute experiments and provide scientific interpretation of results
• Generate plasmids for the expression of membrane proteins
• Express membrane proteins in CHO cells and formulate into nanodiscs
• Characterize nanodiscs by ELISA, gel electrophoresis, and size exclusion chromatography

Minimum Qualifications

Education, Certifications & Experience

• Undergraduate rising senior and graduate students in accredited universities
• Must be pursuing a degree in Biology, Molecular & Cell Biology, or Biochemistry
• Minimum GPA of 3.0

Knowledge, Skills and Abilities

• Cloning
• Mammalian cell culture
• Size exclusion chromatography
• SDS-Page
• ELISA
• Western Blot
• Protein expression in mammalian systems

MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email info@macrogenics.com or call (301) 354-3566 and/or 711 for TTD/TTY service.

Equal Opportunity Employer/Veterans/Disabled

We do not accept non-solicited resumes or candidate submittals from search/recruiting agencies.