Protein Production Technician

Job ID: req3943
Employee Type: nonexempt full-time
Division: Cancer Research Technology Program
Facility: Frederick: ATRF
Location: 8560 Progress Dr, Frederick, MD 21701 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

PROGRAM DESCRIPTION

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. The Protein Expression Laboratory (PEL) provides protein production for the National Cancer Institute Division of Cancer Treatment and Diagnosis (DCTD) in support of a variety of projects related to canine immunotherapy. The PEL creates expression constructs, expresses the encoded recombinant proteins in multiple expression systems, and purifies the recombinant proteins for use in downstream applications including immunoassays, antibody production, and assay development.

KEY ROLES/RESPONSIBILITIES

• Carry out experiments, under the review of a scientist, in the area of eukaryotic protein purification
• Perform microscale protein purification scouting
• Perform large-scale protein purification using FPLC technology
• Perform cell culture on insect and mammalian cell lines
• Carry out extensive quality control on proteins to ensure high-quality reagent production
• Provide timely updates of project progress to supervisor and other staff in both informal and formal reports
• Maintain detailed records of all laboratory processes and procedures for quality assurance purposes

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Possession of Bachelor’s degree in Biochemistry, Chemistry, Biology, or a related field from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency
• No work experience required with a Bachelors degree
• Excellent oral and written communication skills
• Ability to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:

• Ability to handle multiple scientific projects with a high degree of accuracy
• Experience in protein purification
• Experience with microbial or eukaryotic cell culture

Commitment to Diversity
All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.
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