About Us

Jnana Therapeutics is a biotechnology company utilizing a next generation chemoproteomic platform to address well-validated but hard-to-drug targets, including the solute carrier (SLC) family of metabolite transporters. Jnana is focused on developing best-in-class therapies to treat a wide range of diseases, including rare genetic and immune-mediated diseases in addition to oncology. Headquartered in Boston, Jnana is founded by world-renowned scientists and backed by leading life science investors. For more information, please visit www.jnanatx.com and follow us on Twitter and on LinkedIn.

Position description

Jnana Therapeutics is seeking an exceptional, experienced Medicinal Chemist to join our internal chemistry group focused on drug discovery programs for SLCs and other hard-to-drug targets. Through small molecule screening using our novel and proprietary chemoproteomics RAPID platform, our research aims to identify novel small molecules against these challenging targets - to interrogate target biology and ultimately to develop drug candidates that can provide clinical value to patients. Significant prior drug discovery, program experience necessary. Strong commitment to excellence and passion for drug discovery and development are essential. Level can be flexible based on experience. 

Responsibilities

• Provide medicinal chemistry expertise to drive programs from hit generation to clinical candidate selection using state of the art design principles and strategies.
• Work collaboratively across scientific disciplines on multiple projects.
• Work closely with external chemistry CRO teams to synthesize and screen target molecules.
• Proactively engage in brainstorming and the generation of new ideas across projects.
• Assist in preparing patent applications and publications.
• Provide mentorship to Chemistry project leaders and Research Associates.

Preferred Qualifications & Past Experience

• PhD and post-doctoral experience in Organic Chemistry
• 3-5 years of industry experience as a Medicinal Chemist
• Highly organized, detailed-oriented with excellent communication skills