Lung Cancer Global Development Lead, Executive Director

Immunocore is a pioneering biotech with a collegial atmosphere and a passion for harnessing every individual's unique set of skills in our fight against disease.

At Immunocore, we have a vision to transform the way we understand and treat the most challenging medical conditions of our time, including cancer, autoimmune disorders and infection. In January 2022, in the U.S., we launched the world's first T-cell receptor therapy, built on a novel technology designed to overcome the limitations of our natural immune systems.

Joining us at the most exciting time in our history, you will be part of a team that values trust and innovation, and that cherishes different ways of thinking.

The Role:

This is a unique role to develop and lead the end-to-end lung cancer strategy across the portfolio for Immunocore, the only commercial stage T cell receptor company. The Lung Cancer Global Development Lead will report to the Chief Medical Officer and is primarily responsible for the strategy, design and execution of the early and late-stage lung clinical stage programs. The individual will also lead relevant health authority interactions and provide strategic lung cancer perspective to target discovery and translational medicine. They will lead cross functional lung cancer clinical trial teams, including clinical trial design and execution, data interpretation, and presentation. Key will be representing Immunocore externally and leading all interactions with a diverse range of global, scientific and clinical lung cancer experts. As Immunocore is a nimble commercial stage biotech, they must have a 'player-coach' mentality and be able and willing to balance leading a team strategically and, if needed, assume an individual contributor role on a protocol.

Responsibilities:

• Lead the lung cancer strategy for Immunocore, from discovery through registration in close collaboration with other key leaders from Research, Regulatory, Portfolio Strategy, Translational Medicine, Medical Affairs and Commercial.
• Serve as the internal lung cancer expert for the company.
• Lead cross functional team(s) to design and execute innovative Ph1-3 lung cancer trials, from trial concept, site selection, data collection and analyses, ongoing safety review, clinical interpretation, publication and, where appropriate, regulatory submission.
• Builds strong relationships with external lung experts, including SABs, collaborations and maintains high level and standard of scientific and clinical knowledge in lung cancer.
• Complies with all governing laws and regulations, SOPs and any other guidelines as required.

This role may have supervisory duties associated with it and they are noted below:

• Lead matrix clinical development teams comprised of indirect reports.
• Oversight of direct report(s), including direction and support to ensure consistent approach and process to study execution and procedures amongst various program assets.

Experience & Knowledge:

Essential

• At least 5 years biopharma experience, including experience in clinical trial development.
• Expertise/deep understanding of the lung cancer landscape, including current and emerging treatments.
• Designing and leading late phase lung cancer trials, including knowledge of relevant endpoints.
• Leadership of matrix teams.
• Established connections with global lung KOLs.

Desirable

• Working with relevant functions to develop a strategy.
• Experience with health authority negotiations.
• Participated in BLA/MAA.
• Experience in Phase 1 and 2 clinical trials.
• IO experience, including anti-PD(L)1.
• Understanding of translational medicine and integration with IO development.

Essential Competencies

• Demonstrated ability to prioritize in the face of multiple competing priorities.
• Able to lead at least 3-5 Clinical trials of low to moderate complexity or 1-2 trials of high complexity.
• Thorough understanding of clinical research methodology and biostatistics principles.
• Must work with professional discretion and confidentiality.
• Ability to work independently and think outside the box and problem-solve clinical trial issues.
• Result and deadline orientated.
• Excellent presentation skill.
• High credibility.

Education & Qualifications:

• Medical Degree with board certification (or equivalent) in oncology.
• Expert in lung oncology clinical drug development.
• Documented academic and/or clinical research publication history or history of medical practice in a medical field.
• Training and experience working in Immunotherapy is highly desirable.
• Strong working knowledge of the clinical drug development process with experience in the conduct/participation of clinical trials.
• Demonstrated ability to critically evaluate medical/scientific information.

Lead with Science and Discover What is Within:

• We value Entrepreneurship and Diversity
• Respect, Trust, and Integrity
• Competitive compensation
• Medical benefits, beginning your first day of employment
• Vision benefits
• Fully paid Dental Insurance
• 20 days' vacation plus holidays
• Fully paid Life Insurance and Disability
• 401(k) with Company Match

Candidates must be eligible to work in the U.S. without company sponsorship, now or in the future, for employment-based work authorization. F-1 visa holders with Optional Practical Training (OPT) who will require H-1B status, TNs or current H-1B visa holders will not be considered. H1-B and green card sponsorship is not available for this position.

Immunocore is an E-Verify employer.

Applicants have rights under Federal Employment Laws:

Family and Medical Leave Act

Equal Employment Opportunity Commission

Employee Polygraph Protection Act

Uniformed Services Employment and Reemployment Rights Act (USERRA)

Right to work

EEO is the Law Supplement

Pay Transparency