We are currently seeking a Research Specialist to join the lab of Dr. Scott Sternson at The University of California, San Diego. The Sternson lab's research investigates how the brain controls appetite. They study multiple circuits throughout the brain as well as the interactions between neural systems that mediate hunger, thirst, stress, and addiction. Critical to this effort, the lab develops novel chemogenetic methods based on engineering ion channel-ligand interactions. Their goal is to use these detailed chemogenetic tools to develop research and gene therapy tools for obesity, addiction, and other neurological disorders. The lab also uses electrophysiology for optogenetic neural circuit mapping to characterize the synaptic connections between molecularly defined cell types involved in motivated behaviors. More information can be found on their website

In this role, you will be integral to the functioning of the lab and will assist the ongoing research focused on ex vivo patch clamp electrophysiology. In partnership with other researchers in the lab, in this role you will manage electrophysiological rigs, cellular transfection with ion channels, whole cell recordings in HEK cells, acute neuron cultures, and acute brain slices. You will also perform data analysis.

We are looking for a self-driven individual who is eager to implement modern whole cell electrophysiology techniques within the Sternson Lab and expand on their current skillset.

• A competitive compensation package, with comprehensive health and welfare benefits.

• Successful projects in which the candidate participates may lead to authorship on scientific publications.

• One-on-one mentorship.

• A vibrant and inclusive cultural environment.

• Cutting-edge research at the interface between neuroscience and physiology.

• Opportunity for broad interactions with other labs and the scientific community.

• Manage electrophysiology rigs.

• Perform cell culture and cellular transfections to express ion channel transgenes for electrophysiology experiments.

• Perform whole cell electrophysiology experiments on ligand-gated ion channels.

• Perform whole cell electrophysiology experiments for characterizing synaptic connectivity between molecularly defined cell types in brain slices from mice.

• Analyze imaging data and interpret results.

• Work both independently and collaboratively with other team members to support the science of the lab.

• Potential for contributions to scientific publications.

• Master's degree in Biophysics, Biology, or a related field, or equivalent education and experience.PhD preferred but not required.

• Extensive experience with whole cell patch clamp electrophysiology.

• Some programming experience a strong plus for experiment control and data analysis.

• 1-5 years previous experience working in a hands-on research lab.

• Ability to work both independently and in a team setting.

• Good organizational and analytical skills, excellent fine motor skills, and strong attention to detail.

• Ability to follow protocols and maintain a detailed laboratory notebook.

• Willingness to learn.

• Knowledge of Matlab.

Compensation and Benefits

Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our site to learn more.

Compensation Range

Pay Type:

HHMI's salary structure is developed based on relevant job market data. HHMI considers a candidate's education, previous experiences, knowledge, skills and abilities, as well as internal equity when making job offers. Typically, a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range.