The Senior Fermentation Scientist will join our Upstream Bioprocess Development team and will be responsible for the design & execution of fermentation experiments for development of new bioprocesses. The person will play a leading technical role in project management of fermentation programs within the group. In addition, the Sr. Scientist will be responsible for tech transferring bioprocesses to CRO/CMOs. They will collaborate cross-functionally with members of the Technical Operations team. The position will be on-site in Redwood City.

If any of the below describes you, we would love to meet you!

• Passionate about Fermentation and the role it plays in translating scientific discovery into commercial reality.
• Enjoys cross-functional collaboration, teamwork, and mentorship. In addition, has a passion for technical project management.
• Enjoys fermentation process development and microbial physiology (E. coli focus)
• Strong safety mindset in a fermentation environment and have a strong attention to detail.

In this role you will be responsible for:

• Lead the development of new fermentation bioprocesses utilizing E. coli as an expression host for production of enzymes for Pharmaceutical Manufacturing & Life Science applications.
• Hands-on running bench-scale bioreactors (250 mL, 2 L, & 10 L), performing bench experiments, and providing mentorship/management to other team members within the bioprocess group.
• Lead the authorship of tech transfer packages and transferring processes to CRO/CMOs.
• Perform Design of Experiments (DOEs) and data analysis with strong scientific and statistical rigor.
• Supervising Research Associates & Engineers in the bioprocess development group.
• Following safety best practices and leading implementation of new safety processes.
• Routinely present technical information to various audiences both internal and external to Bioprocess Development.

The essential requirements of the job include:

• Ph.D. in Chemical Engineering, Microbiology, Microbial Physiology, or related discipline with a minimum of 5 years of relevant industry experience; M.S or B.S. with at least 8-10 years relevant experience, respectively.
• Strong understanding of microbial physiology (with a focus on E. coli) and its intersection with fermentation processes at bench scale (≤10L).
• Previous hands-on experience with bench scale fermentation for production of recombinant proteins in E. coli.
• Experience with leading multiple fermentation-focused projects simultaneously and technical program management.
• Experience utilizing graphical software (JMP, R, Python, or similar) and motivated in handling large data sets from high throughput fermentation platforms to make data-driven decisions.

Additional experience that would be valuable for this role includes:

• Previous experience working with and providing oversight to CRO/CMOs.
• Experience working under a quality system (e.g. ISO, GMP) or manufacturing experience/exposure.
• Hands-on experience with primary recovery of enzymes and knowledge of downstream purification unit operations.
• Knowledge of automation systems and using liquid handling equipment and assays to support fermentation process analytics.
• Experience managing/mentoring Engineers, and Research Associates performing fermentation process development workflows.