Global Solutions Network (GSN), a federal government contracting firm, presents this full time, long-term position supporting GSN's customer at the National Institutes of Health (NIH). This position provides a competitive salary and comprehensive benefits.

If interested, please provide an up-to-date resume.

Responsibilities.

• Work with staff on performing various experiments and procedures related to differentiation and phenotyping of induced pluripotent stem cell (iPSC) lines 
• Perform standard immunological techniques, including western blotting and immunostaining 
• Operate laboratory equipment to analyze samples 
• Work with staff to characterize genetic pathways for Alzheimer’s disease and related dementia (ADRD) using human cell-based models
• Work with staff to provide insight into the effects of ADRD-associated mutations on molecular readouts in cell culture
• Work with staff to apply published protocols for cell differentiation to iPSC lines, microscopy, and molecular analysis.
• Program, operate, and implement novel methods on liquid handling platforms (Hamilton, Tecan)
• Work with staff on performing large-scale iPSC cell culture experiments on liquid handling platforms.
• Support other research projects
• Collaborate with other team members to carry out large-scale cell culture protocols using high-throughout robotic systems
• Maintain laboratory equipment
• Analyze laboratory findings
• Train staff on the proper usage of laboratory instruments and equipment
• Provide assistance to laboratory staff in designing experiments, using instrumentation, data acquisition and analysis, and preparing figures for publication
• Work as part of a team to provide upkeep of scientific equipment and resources including reagents, stocks of frozen sells, animal samples including acquisition, documentation, and storage.
• Program and use computers to store, process, and analyze data
• Monitor operational procedures in technical environments to ensure conformance to standards
• Interpret research or operational data
• Record research or operational data
• Develop new automated differentiation protocols for iPSC lines to differentiate into disease-relevant cell types like neurons, astrocytes, and microglia
• Develop image analysis routines to analyze the effects of disease-associated mutations on cellular phenotypes

Qualifications.

• Master’s degree in a cell biology, neurobiology, or related discipline
• Proficiency in Microsoft PowerPoint, Excel, and Word
• Minimum of two (2) years of related experience
• Experience with human iPSC culture and automated platforms
• Experience in scripting/coding to create, test, and perform new methods in automated cell culture platforms (basic Venus-based method scripting for Hamilton robot would be very much appreciated)
• Knowledge of proper laboratory disposal methods and procedures 
• Strong scientific communications skills, both oral and written
• Strong general communications skills, both oral and written
• Ability to be a team player in a large research institutes.
• Excellent analytical, organizational and time management skills

Global Solutions Network, Inc. (GSN) is an Equal Employment Opportunity (EEO) employer. It is the policy of the GSN to provide equal employment opportunities to all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected US veteran or disabled status, or genetic information.