About Generate Biomedicines

Generate Biomedicines is a new kind of therapeutics company – existing at the intersection of machine learning, biological engineering, and medicine – pioneering Generative Biology™ to create breakthrough medicines where novel therapeutics are computationally generated, instead of being discovered. Generate has built a machine learning-powered biomedicines platform with the potential to generate new drugs across a wide range of biologic modalities. This platform represents a potentially fundamental shift in what is possible in the field of biotherapeutic development.

We pursue this audacious vision because we believe in the unique and revolutionary power of generative biology to radically transform the lives of billions, with an outsized opportunity for patients in need. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

Generate was founded in 2018 by Flagship Pioneering and has received over $420 million in funding, providing the resources to rapidly scale the organization. The Company has offices in Somerville and Andover, Massachusetts with over 250 employees.

The Role:

The Therapeutic Research team at Generate is expanding! We are seeking a self-motivated Associate Director, Autoimmune Disease Research to oversee cutting edge preclinical research to drive forward autoimmune therapeutic programs at Generate Biomedicines. The successful candidate will lead the autoimmune therapeutic area strategy and lead a team of scientists and RAs to advance autoimmune targeted therapeutics and unlock novel biology using our ML-based approach to drug development. We are searching for an innovative and highly-motivated individual who is comfortable working in a fast-paced, entrepreneurial environment. The position requires interfacing across numerous functions including clinical, commercial, regulatory, tech ops, and project management, as well as protein and computational sciences. The successful candidate will have extensive experience guiding therapeutic research, including direct experience with regulatory filings and translating protein-based therapeutics to the clinic. The candidate should have a sustained record of being a strategic thinker, deep scientist, and a thoughtful people leader.

Here's how you will contribute:

• Lead the Autoimmune Disease group to identify and build new therapies for treating autoimmune disease.
• Advance therapeutic leads through key preclinical milestones in partnership with members of the team, including scientists and research associates.
• Be a resource for end-to-end research advancement (target identification through Phase 1).

• Think ahead to identify program risks and scientific issues, and build and execute plans to mitigate risks for program advancement.
• Be a leader for preclinical preparation of regulatory documents including IND and BLA submissions and experienced in response to Health Authority queries related to preclinical studies.
• Thoughtfully balance business deliverables, scientific opportunities, and team resources to create and sustain a productive and high functioning team.
• Provide scientific and strategic leadership to the Autoimmune Disease group as well as cross-functionally.
• Assist in creating a strong inventive and creative culture with a clear sense of urgency for providing transformational therapies to patients.

The Ideal Candidate will have:

• PhD/9 years of experience in immunology or related scientific discipline and in-depth experience in an industry setting.
• Strong track record in the discovery and development of new autoimmune therapies including leading project teams and contributing to Pre-IND, IND, and other regulatory filings.
• Ability to set strategy and lead research projects by planning, designing, and executing multiple, complex research projects that support corporate scientific goals and priorities.
• A strong leader as evidenced by internal consulting, mentoring, and project team leadership and active support.
• Maintain expertise through review of current scientific literature, submissions to scientific journals, and attendance and participation at conferences.
• Demonstrated excellence in a wide array of scientific techniques and methodologies.

Who Will Love This Job:

• A go-getter who embraces new opportunities and complex challenges with a sense of urgency, high energy, and enthusiasm.
• Someone who operates effectively in a team environment, and who leads with trust, transparency and a collaborative mindset
• A deep scientist who relies on a mixture of analysis, wisdom, experience, and judgement when making recommendations on what to pursue and what not to pursue.

Generate Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

COVID Safety:

Generate Biomedicines enforces a mandatory vaccination policy for COVID-19. All employees must be fully vaccinated and have received a booster. The purpose of this policy is to safeguard the health of our employees, their families, and the community at large from infectious disease that may be reduced by vaccinations. The company will make exceptions to this policy if required by applicable law and will consider requests for an exemption from this policy due to a medical reason, or because of a sincerely held religious belief, or any other exemptions that may be recognized by applicable.

Recruitment & Staffing Agencies: Generate Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate Biomedicines or its employees is strictly prohibited unless contacted directly by Generate Biomedicines's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate Biomedicines, and Generate will not owe any referral or other fees with respect thereto.

#LI-RT1