Gateway Institute for Brain Research, LLC

Job Type: Full-time

Ability to commute/relocate:

This position is based at the Gateway Institute for Research offices and laboratory in the Center for Collaborative Research on the Nova Southeastern University campus in Davie, FL and is an onsite work environment.

Gateway Institute for Brain Research is an international cutting-edge clinical-stage research center dedicated to improving the quality of life for those diagnosed with Parkinson’s Disease, and other neurological conditions. The mission of Gateway Institute for Brain Research is to cure Parkinson’s Disease. We approach this mission through a combination of in-house research, private sponsorship, and inter-institutional collaboration with the goals of expediting the development of novel treatments and fostering scientific understanding.

Position Description:

Gateway is seeking a self-motivated and creative scientist with superior organizational skills to participate in the expansion of its cellular modeling and screening capablities. The candidate will work closely with colleagues within the laboratory and with members of cross-functional teams to move projects forward according to specific goals and timelines.

The goal of the laboratory is to test interventions aimed at reducing or eliminating Parkinson’s Disease-related cellular injuries. The in vitro lab works closely with the Gateway computational biology and modeling teams to identify potential molecules and targets for in vitro testing. This work involves development and validation of cellular models of PD and cellular injury. Cell models include various cell lines, cell co-culture models, and patient-specific iPSC-derived neurons. The laboratory is also responsible for the development and validation of analytical assays to monitor cell state, injury and response to injury. These assays in use include ELISAs, enzymatic assays, western blots, PCR, Mass Spectrometry-based assays, Flow Cytometry, Immunohistochemistry, immunofluorescence, Agilent Seahorse assays, bulk and single-cell RNA-Seq, etc. Candidate interventions with successful outcomes are transferred to Gateway’s Translational team for pre-clinical and clinical testing.

Job Responsibilities:

• Develop, validate and execute analytical assays, including, but not limited to, ELISAs, enzymatic assays, western blots, PCR, Mass Spectrometry-based assays, Flow Cytometry, Immunohistochemistry, immunofluorescence, Agilent Seahorse assays, bulk and single-cell RNA-Seq.
• Contribute to collaborate in the development and validation of in vitro cellular models of PD and cellular injury.
• Collaborates with other scientists in determining the order of research processes that best support essential project goals.
• Collect and summarize experimental data, prepare reports and presentations including basic statistical analyses.
• Ensure that all laboratory work is clearly documented in compliance with company policies and regulatory requirements.
• Organize, clean and monitor laboratory and maintain supplies inventories.
• Maintain laboratory equipment in good working condition.
• Displays professional behavior and ethics in all aspects of job performance.
• Performs other appropriate duties as assigned or required.

Qualifications:

• Masters or Ph.D. degree in biology, chemistry, or other relevant science.
• 5 years of laboratory experience in the field of cellular biology, biotechnology, pharmacology/pharmaceutics and/ or related research experience. Industry experience is a plus.
• Must have a solid understanding of laboratory techniques, experimental design, equipment, and safety.
• Good mathematical, instrumentation, and documentation skills.
• Experience with Google Suite and Graphpad software preferred.
• Ability to give and follow written and oral instructions and to communicate effectively.
• Experience in:Western blotting.

Mammalian cell culture.Microscopy, including confocal.RT-qPCR.Plate readers and high-content imaging.

Benefits:

Following 90 days of employment the following benefits are available:

● Health Insurance

● Dental Insurance

● Vision Insurance

● 401(k)

● Life Insurance

● Short Term / Long Term Disability Insurance

● Paid time off

Job Type: Full-time

Pay: $65,000.00 - $80,000.00 per year

Experience level:

• 5 years

Schedule:

• Monday to Friday

Work Location: In person