Fusion Pharmaceuticals (NASDAQ: FUSN) is a clinical-stage oncology company focused on developing next-generation radiopharmaceuticals as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion’s clinical portfolio includes: FPI-2265 targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial; FPI-1434 targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; and FPI-2059, a small molecule targeting neurotensin receptor 1 (NTSR1), currently in a Phase 1 trial. In addition to a robust proprietary pipeline, Fusion has a collaboration with AstraZeneca to jointly develop novel targeted alpha therapies (TATs) and combination programs between Fusion’s TATs and AstraZeneca’s DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. Fusion has also entered into a collaboration with Merck to evaluate FPI-1434 in combination with Merck’s KEYTRUDA® (pembrolizumab) in patients with solid tumors expressing IGF-1R. To support Fusion’s growing pipeline of TATs, the company has signed strategic actinium supply agreements with TRIUMF, Niowave, and BWXT Medical.

Position Summary

Under the direction of the Senior Director, Radiation Sciences and Molecular Imaging, the Associate Director/Director, Radiation Sciences and Molecular Imaging will work collaboratively with internal team members of the Radiation Sciences team as well as work cross functionally with other divisions within Fusion, including but not limited to Clinical Operations, Non and Per- Clinical teams, Pharmacometrics, DMPK and Regulatory affairs. Additional, working with and helping manage external vendors and contractors to provide support to on going and upcoming clinical trials will also be required of the position.

Responsibilities

• Review and optimization of nuclear medicine imaging protocols, including review of parameters for QC, image acquisition and reconstruction, radiation dose determination, and protocol dose management.
• Set the requirements for the execution of imaging at clinical sites, including providing technical support to study sites.
• Design quality control protocols and collaborate with in-house and external resources for imaging review and processing.
• Provide training, teaching, and problem-solving solutions to internal and external clinical study teams to meet the needs of the study.
• Perform image-based patient specific dosimetry calculations (internal dosimetry not EBRT).
• Partner with team in the design quality control protocols and collaborate with in-house and external resources for imaging review and processing.
• Collaborate with Radiation Science team on the review and optimization of nuclear medicine imaging protocols, including review of parameters for QC, image acquisition and reconstruction, radiation dose determination, and protocol dose management.
• Collaborate with Radiation Science team with radioactive materials regulations or guidelines from regulatory organizations and professional organizations, (e.g., SNMMI, NRC, and other country regulatory bodies)
• Willingness to travel when needed (10-20%)

Qualifications

• The medical physicist should have a bachelors. degree in physical sciences, mathematics or other physical sciences followed by a graduate degree (M.S. or PhD) in medical physics, physics or related scientific disciplines.
• Medical physics residency/Post Doctoral training with 2-5 years of clinical experience/exposure. Board certification is preferred but not required.
• Experience with radiopharmaceuticals, Nuclear Medicine, SPECT and PET imaging techniques, reconstruction, and camera quality control procedures are preferred.
• Strong concepts in radiation biology and radiation physics are preferred.
• Knowledge and Experience with personalized dosimetry for radiopharmaceuticals, experience with programs such as Olinda, MIM and other imaging and dosimetry packages is required.
• Advanced technical computer skills and thorough understanding of modern electronic infrastructures relevant to radiological imaging such as DICOM, PACS is required and, client/server architectures and image processing is preferred.
• Understanding of imaging-related project needs as expressed in a clinical study protocol.
• Prior industry experience is preferred but not required.
• Experience with radioactive materials regulations or guidelines from regulatory organizations and professional organizations, (e.g. AAPM, SNMMI, NRC, and other country regulatory bodies)

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.