You haven't searched anything yet.
Research Assoc I, Pre Clin
Job ID: req3409
Employee Type: exempt full-time
Division: Laboratory Animal Science Program
Facility: Frederick: Ft Detrick
Location: PO Box B, Frederick, MD 21702 USA
The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.
Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.
PROGRAM DESCRIPTION
The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused on the design, generation, characterization and application of genetically engineered and biological animal models of human disease, which are aimed at the development of targeted diagnostics and therapies. LASP contributes to advancing human health, developing new treatments, and improving existing treatments for cancer and other diseases while ensuring safe and humane treatment of animals.
The Mouse Model Core (MMC) Laboratory is comprised of a dynamic team of technical professionals that support the scientific community with the generation of genetically engineered mice (GEM), offering a complete array of services aimed at the successful generation of transgenic and gene-targeted mice, and their expansion and cryopreservation. The Pronuclear injection is an all-encompassing service, covering all the steps from receipt of a recombinant DNA construct containing the transgene of interest to the delivery of breeding-age transgenic founder mice. The gene targeting service is an all-inclusive service that is initiated with electroporation of the vector of interest into the embryonic stem cells (ESCs), followed by production of germline progeny. Other services offered by the MMC Laboratory include: Generation of large cohort of GEMs for experimental use, microinjection of targeted mouse ESCs into blastocysts, de novo generation of ESCs from established mouse models, strain reconstitution from cryopreserved germplasm, rederivation of mouse strains to Specific Pathogen-Free (SPF) status. In addition, the MMC laboratory is responsible for cell culture services that include the receipt of tumor cell lines and submission for MTBM, tumor dissociation, culture and expansion of cell lines for planned experiments, isolation of primary cells from mouse tissue, cryopreservation of stock vials for long-term storage, and preparation of cell lines for injection and transplantation.
KEY ROLES/RESPONSIBILITIES
The Research Associate I will be responsible for mouse embryo manipulation, microinjection, and performance of other molecular biology procedures within the MMC.
BASIC QUALIFICATIONS
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
PREFERRED QUALIFICATIONS
Candidates with these desired skills will be given preferential consideration:
JOB HAZARDS
Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)
#readytowork
Full Time
$68k-88k (estimate)
03/26/2023
05/17/2024