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Principal Scientist - Medicinal Chemistry
About Us: Entact Bio is a preclinical stage biotechnology company developing a new class of drugs that enhance the function of beneficial proteins. Launched by a founding team deeply rooted in deubiquitinase (DUB) biochemistry, chemical biology, disease biology, and small-molecule drug development, Entact has designed its proprietary Encompass™ platform to create enhancement-targeting chimeric (ENTAC™) medicines. ENTACs harness the ability of DUBs to regulate proteins. By leveraging this natural cellular mechanism to enhance protein function, Entact is expanding the universe of treatable diseases.
We are seeking a medicinal chemist to join the Molecular Discovery group. The successful candidate will be accomplished in the field of organic synthesis with a strong background and experience in a wide range of modern synthetic chemistries. They will have a demonstrated ability to design new synthetic, drug-like molecules independently and in a hypothesis-driven manner. The successful chemist will help develop the molecular basis for our Encompass™ platform while interfacing with a team of scientists in mechanistic biology, biophysics and biochemistry, structural biology, computational, and translational sciences to bring forward new therapies.
Responsibilities:
Who You Are:
Qualifications:
Entact is home to scientists, entrepreneurs, drug creators, and problem solvers, all inspired by the idea that even when you’re ill there’s something intact within your cells that can help you get well. As a member of this diverse and growing team, you will lend your insights, passion, and talent to the mission of translating this vision into novel therapeutics for the patients who need them the most.
We are an equal opportunity employer. We will not tolerate discrimination on the basis of race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran's status, pregnancy, genetic information or on any basis prohibited by federal, state or local law.
Full Time
$112k-141k (estimate)
04/05/2024
06/30/2024