Cambridge Isotope Laboratories, Inc. (CIL) is seeking multiple Senior R&D Chemists to join our R&D team based onsite in our Andover, MA location with eventual relocation to our Ames Pond Facility in Tewksbury, MA. The newly created R&D team will focus on driving the development of new products, process optimization, custom synthesis support, and evaluation of new technologies.

The Senior R&D Chemists perform de novo synthesis, route development and final product characterization of a wide variety of complex isotopically labeled (13C, 15N, 18O and D isotopes) targets. They are responsible for developing and optimizing manufacturing procedures following CIL’s safety and general policies. Working with a high degree of independence, Senior R&D Chemists are required to meet production requirements with respect to safety, yield, time, and quality.

Responsibilities

• Comply with CIL’s general and safety policies.
• Synthesize complex, non-routine and/or routine target compounds generally containing 15N, 18O, D and/or 13C, in some instances using established SOPs.
• Design and develop new synthetic routes as necessary.
• Contribute to optimization of chemical routes to the targeted molecules and intermediates, and scalable, cost-effective processes.
• Analyze and interpret data obtained from nuclear magnetic resonance (NMR), ultraviolet (UV), mass (MS), HPLC and infrared (IR) spectroscopy.
• Utilize purification techniques which include: chromatography, distillation, recrystallization and sublimation.
• Demonstrated ability to work with a team, challenge ideas, and determine best solutions.
• Take accountability for consistent and timely execution of project deliverables.
• Keep an accurate and detailed laboratory notebook.
• Assist other members of the department as necessary.
• Maintain best in class housekeeping.
• Contribute to the continuous improvement of our safety policies and procedures.
• Perform any related work as necessary.