Position Description:

Calico is looking for an exceptional Postdoctoral Fellow to join the Cellular Phenotyping (CP) team. The CP group uses scalable, information-rich methods to catalog and interpret the phenotypic effects of chemical and genetic perturbations to age-related processes and diseases. The selected candidate will design and utilize innovative approaches to study the phenotypic trajectory of differentiating hematopoietic stem cells using live-cell imaging and single-cell genomics. This work offers a unique opportunity for cross-functional collaboration with experts from across Calico in immunology, high-content imaging, and machine learning. The ideal candidate must demonstrate a record of achievement in cell biology or immunology and should be comfortable working on complex problems both independently and as a member of a team.

Responsibilities:

* Contrast the trajectories of hematopoietic stem cell differentiation observed by live-cell imaging with those inferred from single-cell RNAseq

* Present findings internally and externally at conferences

* Prepare manuscripts for publication

Position Requirements:

* PhD in cell biology, immunology, or related field

* Experience with mammalian cell culture, confocal microscopy, live cell imaging, and/or high-content imaging platforms

* Enthusiastic and organized team player with attention to detail and excellent verbal/written communication skills

* Strong record of research productivity with impactful scientific publications

* Must be willing to work onsite at least four days per week

Nice to have:

* Knowledge of immunology with experience in primary immune cell culture

* Hands-on experience with cell biology techniques including multiplexed IF, flow cytometry, FISH, and/or scRNAseq

* Experience with quantitative image analysis and basic machine learning principles

* Competency with Python or R is a plus

The estimated base salary for this role is $95,000.

More information on our postdoctoral fellowship program can be found here.