Research Associate I / II, Bioassay (Potency assay)

Temporary position

WHY WORK FOR ARCTURUS?

Founded in 2013 and based in San Diego, California, Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) is a clinical-stage mRNA medicines and vaccines company with enabling technologies: (i) LUNAR® lipid-mediated delivery, (ii) STARR™ mRNA Technology and (iii) mRNA drug substance along with drug product manufacturing expertise. Arcturus’ diverse pipeline of RNA therapeutic and vaccine candidates includes self-replicating mRNA vaccine programs for SARS-CoV-2 (COVID-19) and Influenza, and other programs to potentially treat Ornithine Transcarbamylase (OTC) Deficiency, Cystic Fibrosis, Cardiovascular Disease along with partnered programs including Glycogen Storage Disease Type 3, Hepatitis B Virus, and non-alcoholic steatohepatitis (NASH). Arcturus’ versatile RNA therapeutics platforms can be applied toward multiple types of nucleic acid medicines including messenger RNA, small interfering RNA, replicon RNA, antisense RNA, microRNA, DNA, and gene editing therapeutics. 

Arcturus’ technologies are covered by its extensive patent portfolio (192 patents and patent applications, issued in the U.S., Europe, Japan, China and other countries). Arcturus’ commitment to the development of novel RNA therapeutics has led to collaborations with Janssen Pharmaceuticals, Inc., part of the Janssen Pharmaceutical Companies of Johnson & Johnson, Ultragenyx Pharmaceutical, Inc., Takeda Pharmaceutical Company Limited, CureVac AG, Synthetic Genomics Inc., Duke-NUS, and the Cystic Fibrosis Foundation. 

Arcturus Therapeutics is presently recruiting outstanding candidates with experience in the field of mRNA technologies and nanoparticle sciences. 

Our corporate culture is dynamic, diverse, and creative. We value collaboration and teamwork. We seek individuals to join us with a genuine passion for the science behind helping to cure disease and improve the lives of patients.

THE OPPORTUNITY

Arcturus Therapeutics is seeking a highly motivated hands-on individual to join our expanding Analytical Development team in the role of Research Associate/Senior Research Associate for Bioassay and Potency assay development. The selected individual will support cell culture based bioanalytical daily workflows (i.e.: Transfections, ELISA, Luminex, MSD, ICW, Jess, etc.), and will be involved in the identification of new potency assays and technologies to advance Arcturus’s pipeline. The successful candidate will possess strong technical skills, and the ability to develop, troubleshoot, and execute bioanalytical assays under minimal guidance and supervision. The candidate is expected to manage multiple projects and to communicate data/reports in accordance with Arcturus’ timelines. This position will directly report to the Bioassay team lead in the Analytical Development Department and will collaborate with other functional groups within the organization.

 WHAT YOU WILL CONTRIBUTE 

• Support multiple programs and platforms within the company.
• Develop, troubleshoot, and execute bioanalytical assays (i.e.: Transfections, ELISA, MSD, ICW, Jess, etc.) to support in vitro and pre-clinical projects. 
• Support tech transfer of methods to CRO and development partners
• Implement new technologies to advance our pipeline.
• Analyze, review, and interpret bioanalytical datasets.
• Provide project summaries/reports in team meetings.
• Perform other duties as assigned.

 WHAT WE SEEK

• BS or MS in cellular and molecular biology, immunology, biochemistry, or other biological relevant disciplines. 
• 2 years industry experience is preferred.
• Require 1-3 years of experience in cell culture techniques
• Experience with in vitro transfection systems for human cell lines is preferred. 
• Experience with Western blot, ELISA, JESS, and MSD. 
• Experience with LNP or mRNA delivery systems is a plus.
• Proven ability to perform and troubleshoot bioanalytical assays.
• Experience in data analysis with Excel, JMP and PRISM is a plus. 
• Excellent written and verbal communication skills, and proven ability to manage multiple experiments.
• Excellent organizational skills, attention to details, and proven ability to work under minimal supervision within a multi-disciplinary environment. 

EDUCATION

• BS/MS degree in cellular and molecular biology, biochemistry, biological sciences, pharmaceutical sciences, chemistry, or other relevant disciplines.

WHAT WE OFFER

Research Associate I :Anticipated salary range for candidates that will work in San Diego is $67,000 – $88,600.

Research Associate II :Anticipated salary range for candidates that will work in San Diego is $77,400 – 102,400.

An exciting opportunity to join a company that offers:

• Catered lunches
• Free variety of snacks and beverages
• Referral Bonuses
• On Campus Gym
• Company sponsored FUN events

For a deeper dive into our company and corporate culture visit www.ArcturusRx.com