HOW MIGHT YOU DEFY IMAGINATION?

If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever–better products that reach over 10 million patients worldwide. Its time for a career you can be proud of.

Process Development Senior Principal Scientist Peptide Chemistry (Synthetics)

What you will do

Lets do this. Lets change the world. Amgen is seeking a dedicated Process Development Senior Principal Scientist with industry experience in peptide synthesis and manufacturing to join our Drug Substance Technologies – Synthetics (DSTS) group in Cambridge, MA. Amgens DSTS group within Process Development (PD) is responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's portfolio of synthetic and hybrid assets. The Senior Principal Scientist role will include leading a multidisciplinary team of chemists and chemical engineers in the development of efficient and sustainable manufacturing processes for peptide synthesis and purification, driving technology innovation in the areas of chemical and microbial recombinant peptide production technologies, and providing technical expertise as well as developing and mentoring staff within the organization. The successful candidate for this role will be a people–centered leader with expertise in peptide process development and manufacturing with a consistent track record of scientific innovation and leadership within the pharmaceutical industry.

• Lead a multidisciplinary project team in the development of sustainable and cost–effective processes for peptide manufacturing
• Drive technology innovation in the areas of chemical and microbial recombinant peptide production technologies
• Support cGMP manufacturing and technology transfer to large–scale peptide production facilities
• Develop strategies to ensure process performance through process understanding, modeling and characterization
• Guide successful completion of project deliverables and ensure timelines are met
• Work multi–functionally to deliver regulatory documents and support regulatory filings
• Serve as a technical expert and keep current in the field of peptide synthesis and manufacturing
• Coach and provide career and scientific / technical advice to colleagues within the organization

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek will possess these qualifications.

Doctorate degree PhD OR PharmD OR MD in Chemistry, Chemical Engineering, or Biochemistry/Chemical Biology and 3 years of industry experience

Masters degree in Chemistry, Chemical Engineering, or Biochemistry/Chemical Biology and 6 years of industry experience

Bachelors degree n Chemistry, Chemical Engineering, or Biochemistry/Chemical Biology and 6 years of industry experience

• 6 years in the pharmaceutical industry with expertise in peptide process development and manufacturing (solid–phase peptide synthesis, liquid–phase peptide synthesis, site–selective peptide modification, semisynthetic approaches, chemoenzymatic peptide synthesis)
• Ability to work within a dynamic and interdisciplinary environment to achieve results
• People–centered leadership skills in building strong teams through mutual trust and respect and exhibits Amgen leadership attributes of inspire, accelerate, integrate, and adapt
• Track record of publications, patents and presentations

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well–being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales–based incentive plan
• Stock–based long–term incentives
• Award–winning time–off plans and bi–annual company–wide shutdowns
• Flexible work models, including remote work arrangements, where possible

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.