What You Will Contribute To Altos

The Altos Institute of Medicine will capture knowledge generated about cell health and programming and develop transformative medicines. We are seeking a highly experienced analytical and QC leader to join the Technical Operations team within the Institute of Medicine. The candidate will work in a highly dynamic and cross-functional environment that will have close collaboration with the Institutes of Science and span multiple therapeutic areas. The successful candidate will lead analytical development and quality control for Altos programs. Modalities include AAV gene therapy, small molecules, antisense oligonucleotides, mRNA and protein therapeutics.

Responsibilities

• Lead analytical development and quality control for AAV gene therapy, small molecules, antisense oligonucleotides, mRNA and protein therapeutics
• Build a high performing team and establish internal and external analytical and QC capabilities
• Manage contract manufacturing organizations and contract testing organizations to develop and qualify analytical testing methods, perform product characterization, release and stability testing, and in-process testing
• Establish product specifications to ensure product quality. Support technical assessment of Out of Specification and Non-Conforming investigations.
• Author, review, and/or approve Standard Operating Procedures, specifications, regulatory filing, or other controlled documents
• As a member of the Tech Ops leadership team, build the Tech Ops organization, processes, systems and infrastructure
• Create and foster strong partnerships with Institutes of Science, development sciences, clinical, regulatory, program management, science integrations, business development, legal and finance
• Actively contribute to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion

Who You Are 

Qualifications

• PhD in Analytical Sciences or Biological Sciences.
• Minimum 15 years of analytical development and QC experience in biotech/pharmaceutical industry. 10 years of Management experience.
• Highly experienced in developing and implementing assays for Quality Control testing and characterization of drug substance, drug product and manufacturing in-process samples
• Experienced in multiple modalities AAV gene therapy, oligonucleotides and small molecules
• Proficient in cGMP’s and pharmaceutical industry procedures and regulations
• Highly experienced in achieving CMC deliverables through outsourcing to Contract Manufacturing Organizations. Leadership experience in managing diverse project activities with contract CDMO facilities at global locations
• A critical thinker with the ability to analyze possibilities and solutions and make pragmatic trade-offs, as well as a big-picture innovator who can identify opportunities and is comfortable with ambiguity
• Strong communication and collaboration skills. Clear and influential communicator. Build effective relationships and partnerships with internal and external stakeholders
• Proven capability to lead, motivate and inspire in a diverse, global, cross-functional structure and commit to diversity, equity, and belonging.

The salary range for Redwood City, CA:

• Senior Director: $289,850 - $392,150

Exact compensation may vary based on skills, experience, and location.

For UK applicants, before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (bit.ly/eu_uk_privacy_notice)
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.

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