This is what you will do:

The Associate Scientist II will join the Injectable Drug Product Development team to support the development of Alexion’s bio-therapeutic candidates. This individual will develop injectable formulations with fit for purpose analytical methods, perform analytical testing, and draft reports for the implemented studies. Work independently with dynamic collaborative team and other members of Injectable DPD and Clinical Supply.

You will be responsible for:

• Execution of formulation screening and stability studies for injectable drug products including proteins, siRNAs, peptides
• Supporting analytical method development and optimization
• Supporting development and tech transfer of GMP fill finish processes to internal and external manufacturing organizations.
• Writing internal technical reports on the implemented studies
• Assisting in preparation of external regulatory submissions for the Alexion product candidates
• Participate in department meetings and other technical and team building activities

You will need to have:

• Hands-on experience on developing phase appropriate formulations and fill finish processes
• Good understanding of protein chemistry and stability, and degradation mechanism
• Ability to work as part of a collaborative team with defined timelines
• Proven track record working successfully in a cross-functional environment
• Hands-on experience with liquid chromatography methods (e.g. SEC, IEX, HIC) and capillary methods (e.g. iCE, LabChip GXII Touch)
• Demonstrated experience with analytical software (e.g. Empower, JMP)
• Experience with electronic record keeping software, like ELN
• The duties of this role are generally conducted in a lab environment. As is typical of a lab-based role, employees are required to, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious, and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours

We would prefer for you to have:

• BS or MS degree in Biochemistry, Chemistry, Chemical Engineering or related field. 1 years for MS or 2 years for BS
• Partnership and interpersonal skills.
• Understanding of the biotechnology products life cycle and factors impacting product stability.
• Knowledge of cGMP and quality guidelines.
• High level proficiency in MS Office software including Word, Excel, Outlook, and PowerPoint

Expectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of four days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.