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AcuraStem is a pre-clinical stage company focused on amyotrophic lateral sclerosis (ALS). AcuraStem is advancing novel therapeutic approaches for ALS using patient-derived stem cell models. The incumbent candidate should have experience in neurobiology, stem cells, familiarity with CNS animal models and the pharmaceutical process of drug discovery.
The principal scientist is expected to work independently but in close cooperation and in consultation with the AcuraStem leadership and other scientists. The principal scientist is responsible for development and execution of bioassays, and pharmacology of AcuraStem's ALS program. This position will play a key role in AcuraStem's therapeutic discovery and development process. The efforts will include including working with key opinion leaders to advance disease-related target engagement and efficacy investigations, ultimately driving to clinical candidate and indication selection.
The principal scientist will be expected to assist in the preparation/submission of multiple grant proposals and also prepare full manuscripts for publication based on their research results. The principal scientist will be expected to maintain establish and maintain institutional IRB/SCRO protocols as well as develop new animal and IACUC protocols.
We are seeking a team player who is persistent, and tenacious with an objective to complete experimental plans with high quality, on time and on budget. The ideal candidate should be extremely well organized in order to document and communicate experimental results clearly and concisely. The candidate will be expected to provide regular updates, documentation, and communication of project results to senior leadership.
The successful candidate will be responsible for performing cell maintenance, expansion and genetic modification of cell models (including stem cells) using viral vectors or other gene-editing methods. A proven record with stem cell culture techniques is important. Prior experience in using pluripotent stem cells is a plus.
RESPONSIBILITIES:
The candidate must already be in the USA and approved to work immediately.
Full Time
Contract Research
$205k-252k (estimate)
05/01/2024
06/29/2024
acurastem.com
Monrovia, CA
<25
Contract Research