Title: Research Associate

Department Org: Medicine - 107570

Employee Classification: J1 - Salaried Full Time HSC

Bargaining Unit: Professional Staff Association

Primary Location: HSC C

Shift: 1

Posted Salary: Salary commensurable based on experience

Float: False

Rotate: False

On Call: True

Travel: True

Weekend/Holiday: True

Job Description:

The person in this position works together with the Principal Investigator to design and carry out research experiments related to the molecular and cellular basis of cancer health disparity and links to metabolic diseases (diabetes and brain degenerative disorders). Specifically we study several novel pathways involving the role of scaffold proteins in nuclear-cytoplasm crosstalk and ER-stress. Perform experiments, analyze data, prepare manuscripts for publication, train and manage laboratory personnel and students, and manage all aspects of the research laboratory. We employ a multifaceted approach, including super-resolution microscopy, color IHC and kinemics. We use cell culture, mouse models and human tissues. Other projects in the lab include drug discovery both targeted and unbiased screens. We collaborate widely with experts in the field.

Minimum Qualifications:

• PH.D. (preferred) or MS degree & 2 years of research experience required.
• Background knowledge in molecular pathogenesis of disease.
• Molecular biology facility management. Must have experience in molecular biology techniques, including the maintenance of PCR thermal-cyclers, centrifuges, spectrophotometers, laminar flow hoods for PCR work, pipets, freezers, storage conditions for samples and reagents, and proper standard operating procedures for molecular biology laboratory.
• Cell culture facility management. At least 1 year of experience managing cell culture facilities, including maintaining certification of laminar flow hoods of cell culture work, maintaining proper function of cell culture incubators, establishing proper standard operation procedures for the culture of both primary and immortal cell lines.
• Experience in light microscopy and immunofluorescence staining on tissues, primary cell cultures and on immortal cell lines. Ability to learn advanced microscopy upon training
• Experience in the maintenance and husbandry of transgenic mice and/or rats and in non-survival mouse and rat surgery for the isolation and culture of primary cell cultures.
• Working knowledge of Microsoft Word, PowerPoint and Excel to include basic computer skills.
• Computer database management with five years' experience establishing and maintaining computer databases for cell culture archives and experimental results, including proper computer backup.
• Successful completion of NIH Protection of Human Subjects, CITI, HIPAA and laboratory safety training is required (may be completed post hire).

Conditions of Employment:

Equal Employment Opportunity Statement:

The University of Toledo is an equal opportunity, affirmative action employer. The University of Toledo does not discriminate in employment, educational programs, or activities on the basis of race, color, religion, sex, age, ancestry, national origin, sexual orientation, gender identity and expression, military or veteran status, disability, familial status, or political affiliation.

The University is dedicated to the goal of building a culturally diverse and pluralistic faculty and staff committed to teaching and working in a multicultural environment and strongly encourages applications from women, minorities, individuals with disabilities, dual-career professionals and covered veterans.

The University of Toledo provides reasonable accommodation to individuals with disabilities. If you require accommodation to complete this application, or for testing or interviewing, please contact the Human Resources Department at 419-530-4747 between the hours of 8:30AM and 5:00PM or apply online for an accommodation request.

Computer access is available at most public libraries and at the Office of Human Resources located in the Center for Administrative Support on the Main Campus of the University of Toledo.