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Staff Business Systems Analyst

Twist Bioscience
South San Francisco, CA Full Time
POSTED ON 1/7/2026
AVAILABLE BEFORE 2/27/2026
Staff System Business Analyst (Hybrid in South San Francisco OR Carlsbad)

About The Role

This role is critical in supporting our enterprise applications landscape, ensuring that our business systems seamlessly support our rapidly scaling biotech operations. As the primary bridge between business stakeholders and technical teams, you will help drive the design, enhancement, and integration of order-to-cash solutions - particularly in connection with Salesforce (SFDC) and SAP - to enable efficiency, compliance, and innovation across multiple business functions.

The salary range posted is based on the South San Francisco location

Key Responsibilities

  • Partner with stakeholders across Finance, Commercial, Manufacturing and Shipping to gather, analyze, and document business requirements.
  • Translate business needs into functional specifications and collaborate with SFDC and SAP developers/configurators to design and deliver solutions.
  • Lead and support cross-functional projects involving SAP and other enterprise systems (including Salesforce), ensuring integration points are optimized and business processes flow seamlessly end-to-end.
  • Support system testing, user acceptance testing, and production deployments, ensuring deliverables meet requirements and compliance standards.
  • Troubleshoot user issues and recommend long-term improvements.
  • Develop and maintain business process flows and training materials.

Qualifications

  • Bachelor’s degree in Information Systems, Computer Science, Business, or related field (or equivalent experience).
  • 8 years of experience as a Business Analyst or Functional Consultant supporting SAP systems.
  • Strong understanding of multiple SAP modules and how they integrate across business functions.
  • Proven experience in SAP - Salesforce (SFDC) integration projects and cross-system business processes.
  • Demonstrated ability to lead cross-functional projects and serve as the liaison between business users and technical teams.
  • Strong problem-solving skills and ability to thrive in a fast-paced, dynamic environment.
  • Excellent communication and stakeholder management skills, with the ability to engage at both technical and executive levels.

Preferred Skills

  • Experience in a biotech, pharmaceutical, or manufacturing environment.
  • Hands-on experience with SAP S/4HANA.
  • Familiarity with GxP, SOX, or other compliance frameworks relevant to life sciences.

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.

San Francisco Bay Area Pay Range

$165,000 - $195,000 USD

Salary : $165,000 - $195,000

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