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Medical Affairs Operations Manager

The Nagler Group
Lexington, MA Contractor
POSTED ON 4/9/2026
AVAILABLE BEFORE 5/9/2026
Medical Affairs Associate Director

Hybrid | Greater Boston Area

Base Salary: $160,000–$180,000 Bonus and Equity

Benefits: Comprehensive benefits package, uncapped PTO

We are partnering with a late-stage, publicly traded rare disease biotech to hire a Medical Affairs Excellence & Operations Lead at the Associate Director level. This is a high-visibility, Chief-of-Staff–style role supporting senior Medical Affairs leadership and playing a critical role in how the function operates and scales.

This opportunity is ideal for a Medical Affairs professional with a strong scientific foundation who enjoys building structure, driving execution, and leading through influence in a fast-paced biotech environment.

About The Opportunity

  • Close partnership with the VP, Global Head of Medical Affairs
  • Strategic, hands-on role with no initial direct reports
  • Opportunity to shape Medical Affairs operations, metrics, and scalability

Key Responsibilities

  • Operationalize Medical Affairs strategy and track execution against objectives
  • Build and maintain KPIs, dashboards, and performance metrics
  • Own multi-million-dollar Medical Affairs budgets, forecasting, and spend tracking
  • Lead vendor selection, contracting, onboarding, and ongoing oversight
  • Coordinate cross-functional initiatives across Medical, Clinical, Commercial, and Compliance
  • Support Medical Affairs launch readiness and scientific conference execution
  • Oversee non-promotional materials and internal review workflows
  • Drive process improvement in a growing, global Medical Affairs organization

Required Qualifications

  • 7 years of experience in Medical Affairs within pharma/biotech (MSL background strongly preferred)
  • Small biotech experience required
  • Proven experience managing multi-million-dollar budgets
  • Strong track record leading cross-functional initiatives in matrixed environments
  • Direct, confident communicator comfortable operating in ambiguity and change
  • Must be East Coast–based; Greater Boston area strongly preferred
  • Interested, or know someone who may be a fit?

Please reach out directly to omckenelley@naglergroup.com for a confidential conversation.

#TNG123

Salary : $160,000 - $180,000

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