What are the responsibilities and job description for the Associate Scientist, Injectable Drug Product Development position at Talent Groups?
Duration: 12 months to start
Job Description
Job Description
- The position is required to join Injectable Drug Product Development group of the client's�Pharmaceutical Development and Clinical Supply (PDCS) department.
- The job entails experimental work on various aspects of drug product characterization, including analytical testing, biophysical comparability testing, and process development to support drug product manufacturing.
- The ability to work with minimal supervision as well as part of the team is essential.
- The position entails execution of the studies, data processing, and compiling to generate development reports as well as other required documentation.
- With some supervision, design and execute development studies for the client s clinical drug candidates and commercial products, characterizing protein drug conformational and colloidal stability using industry standard methodology (e.g., circular dichroism, differential scanning fluorimetry, analytical ultracentrifugation, size-exclusion chromatography with multi-angle light scattering detection, etc.)
- Can prioritize multiple assigned tasks and projects. The ability to work independently as part of the team is essential.
- Execute drug developability studies including physicochemical characterization, UPLC analysis, and stability studies for the client s drug candidates and commercial products
- Assist in preparation of internal technical reports on the executed studies with minimal supervision
- Participate in cross-functional development teams
- BS or MS degree in Biochemistry, Pharmaceutical Science, Chemical Engineering, or relevant field with 0-2 (MS) or 2-4 (BS) years relevant work experience with a pharmaceutical, CRO, CDMO or biotechnology company
- Solid understanding of protein stability, thermodynamics, and mechanism of protein degradation.
- Experience of working with imaged capillary electrophoresis (iCE/Maurice), H/UPLC s (IEX, SEC), DLS, CD, DSC or NanoTemper is desirable.
- The ability to execute experiments with minimal supervision is required.�
- The individual must be able to work in a collaborative setting and having the ability to adhere to timelines is essential.
- Excellent interpersonal, collaborative and communication skills
- Experience with various software packages like MS Office programs, including Word, Excel, Outlook, and PowerPoint
- The duties of this role are generally conducted in a lab environment.� As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video and electronic messaging; engage in problem solving and non-linear thought, analysis and dialogue; collaborate with others; maintain general availability during standard business hours.�
- Experience of working with biophysical testing and analytical testing
- Familiarity with low volume analytical assays.
- High level proficiency in MS Office software including: Word, Excel, Outlook, and PowerPoint.
- Experience with electronic record keeping software, like ELN, EndNote, e-logbooks; maintenance of laboratory instrumentation (organizing PMs, data backup, SW upgrade, etc.) will be a plus.
- Ability to take initiative in problem solving and finding solutions to scientific challenges is preferred.
- The individual must be able to work in a collaborative setting and ability to adhere to timelines is essential.
- Excellent interpersonal skills are required, as is the strong ability to communicate effectively.