Associate Scientist

Role Summary

• As a Scientist (non-PhD) on our ADC Biology team, you will be a key driver in advancing next-generation ADC technologies through collaborative, cross-functional research that spans from early discovery to pre-clinical development.
• Will develop assays and execute screening and identification of novel chemotypes that function as payloads for antibody drug conjugates for cancer therapy. You will work collaboratively with chemistry and other cross functional teams to understand mechanism of action of identified payloads.
• Will analyze, interpret and communicate the data effectively to key stake holders.
• Apply cellular, biochemical, immunological, and molecular biology laboratory techniques to preclinical research projects in the areas of Cancer signaling and Cancer biology
• Investigate MOAs of our therapeutics through development, optimization, and execution of complex assays
• Interact and collaborate with other functional groups across research
• Provide leadership within technical area of expertise; may train, direct or mentor others
• Design and execute key experiments to investigate novel therapeutic targets and MOAs of novel payloads to enable clear go/no-go decisions.
• Independently analyze data, document results, and present findings to large and small audiences
• Maintain rigorous records of experimental progress using electronic laboratory notebooks
• Present experimental results and scientific rationale to colleagues
• Execute molecular, biochemcial and cell-based methodologies including cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling multicolor flow cytometry, immunofluorescence and live cell microscopy.
• Aid in execution and analysis of additional experiments as need arises within the ADC discovery research team
• Role is lab based with a equal amounts of office work. (Lab book entries, Group meetings, Group presentations.)
  
  

Minimum Requirements

• Bachelor's degree in Cellular or Molecular Biology, Immunology, Biochemistry or related field and 6 years' relevant industry experience; OR
• M.S. degree in Cellular or Molecular Biology, Immunology, Biochemistry or related field with 4 years' relevant industry experience
• Experience with Microsoft Office (Excel, Word, PowerPoint) and analytical (Prism, FlowJo, etc.) software programs
• Experience designing, performing and interpreting complex experiments that require significant insight into problems being addressed with some guidance
• Working knowledge in specific areas of Cancer Biology and Cancer therapeutics esp, small molecule agents, Biologics and ADCs
• Experience working independently and working on multiple projects
• Experience collaborating across teams and a variety of disciplines to provide experimental expertise and support others on joint projects
• Experience leading parts of projects or initiatives within area of expertise
• Excellent written/oral communication skills with experience presenting/sharing details of the work with key stake holders
  
  

Preferred Requirements

• Experience in experimental cancer biology, biochemical and/or immunological techniques (e.g., Cell culture, cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling multicolor flow cytometry, immunofluorescent and live cell microscopy.).
• Background knowledge of the field of cell signaling and biochemistry
• Experience developing complex cell and biochemical assays
  
  

Benefits

Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.

Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.

Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.

Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.

Synectics is an equal opportunity employer.