Demo

Senior Researcher

SoTalent
Boston, MA Full Time
POSTED ON 4/20/2026
AVAILABLE BEFORE 5/20/2026

Position Information

Job Title: Senior Research Associate

Location: Cambridge, Massachusetts (with limited remote flexibility)


Role Overview

A global life sciences organisation is seeking a Senior Research Associate to contribute to antibody discovery and development programmes. In this role, you will design and perform laboratory-based research focused on identifying and optimizing therapeutic antibody candidates.


You will be responsible for planning and executing experimental strategies, applying display technologies, and advancing candidates through early discovery and optimisation phases. The position requires a high level of independence, technical expertise, and the ability to interpret complex experimental data.


Key Responsibilities

  • Design and carry out in vitro antibody discovery workflows using display technologies such as yeast or phage systems
  • Perform advanced laboratory experiments independently and contribute to the progression of therapeutic candidates
  • Generate and utilise immune libraries derived from biological sources for discovery purposes
  • Develop and refine libraries aimed at improving antibody characteristics such as affinity, potency, and stability
  • Prepare biological samples for sequencing using modern sequencing techniques and analyse resulting data
  • Conduct cell-based experiments, including mammalian cell culture, immunoassays, and flow cytometry (including cell sorting)
  • Apply molecular biology techniques such as cloning, gene amplification, mutagenesis, and nucleic acid extraction
  • Analyse experimental outcomes, troubleshoot issues, and propose improvements or next steps
  • Support experimental design and maintain laboratory equipment, materials, and documentation
  • Organise and analyse data from collaborative projects, including maintaining records in laboratory information systems


Requirements

  • Master’s degree in a relevant scientific discipline such as Biochemistry, Molecular Biology, Immunology, Biotechnology, or Bioengineering
  • At least 1 year of relevant laboratory or research experience


Required experience includes:

  • Designing and executing antibody discovery strategies using display technologies
  • Constructing and working with biological libraries using molecular biology techniques
  • Managing research projects from early discovery through candidate selection
  • Designing and building genetic constructs for cell line development
  • Developing and applying high-throughput screening assays, including flow cytometry-based methods
  • Hands-on experience in areas such as antibody discovery, molecular biology, or related research fields


Additional Information

  • Full-time role
  • Salary range typically between $86,000 and $148,000 annually, depending on experience and qualifications
  • Hybrid work model with up to approximately 20% remote work
  • Eligible employees may receive additional incentives and a comprehensive benefits package, including healthcare, retirement plans, paid leave, and development opportunities

Salary : $86,000 - $148,000

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