Research Associate II- Antibody Engineering

Software Guidance & Assistance, Inc., (SGA), is searching for a Research Associate II- Antibody Engineering for a contract assignment with one of our premier Pharmaceutical services clients in South San Francisco, CA.

Responsibilities :

The firm's Antibody Engineering Department leverages state-of-the-art approaches and technologies to discover and engineer antibody-based therapies to improve patient well-being. We are seeking a highly motivated and talented individual to join our dynamic and fast-paced environment to support this mission. The primary focus of this hands-on laboratory position will be to implement and apply molecular biology and biochemistry techniques, namely phage display, to support the antibody discovery process. The successful candidate will work closely with Antibody Engineering scientists to deploy the above approaches to help discover novel antibodies for application across broad, multi-functional efforts geared towards therapeutic development.

• Generate antibody phage display libraries and perform in vitro selections to identify candidate binding clones.
• Interface with colleagues within Antibody Engineering to understand and address program needs to inform selection strategies.
• Use high-throughout biochemical techniques (e.g. ELISA, surface plasmon resonance) to rigorously characterize antibody candidates.
• Deploy molecular biology approaches (e.g. PCR, cloning) to enable rapid recombinant expression of candidate clones.
• Maintain and share detailed records of results for facile transfer of binding clones to program teams for further characterization.
  
  

Required Skills:

• B.S./B.A. degree or higher in biology, chemistry, or related field
• 5-10 years of relevant industrial experience, ideally in a drug discovery setting
• Basic biochemistry and/or molecular biology lab skills, including:
• RNA isolation
• Bacterial culture
• Phage display - PCR and ELISA (not required, but would set a candidate apart. This is the primary function of this role, but RRP is willing to train the right candidate)
• Molecular cloning and DNA/protein sequence analysis
• Experience with Microsoft Excel, Microsoft Powerpoint.
• Excellent record keeping and communication skills.
• Excitement and enthusiasm to work in a dynamic, collaborative, and fast-paced environment.
  
  

Preferred Skills:

• Experience measuring protein-protein interaction binding affinity using surface plasmon resonance is a plus.
  
  

SGA is a technology and resource solutions provider driven to stand out. We are a women-owned business. Our mission: to solve big IT problems with a more personal, boutique approach. Each year, we match consultants like you to more than 1,000 engagements. When we say let's work better together, we mean it. You'll join a diverse team built on these core values: customer service, employee development, and quality and integrity in everything we do. Be yourself, love what you do and find your passion at work. Please find us at https://sgainc.com/ .

SGA is an Equal Opportunity Employer and does not discriminate on the basis of Race, Color, Sex, Sexual Orientation, Gender Identity, Religion, National Origin, Disability, Veteran Status, Age, Marital Status, Pregnancy, Genetic Information, or Other Legally Protected Status. We are committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, and our services, programs, and activities. Please visit our company EEO page to request an accommodation or assistance regarding our policy.